Actively Recruiting
Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery
Led by Ain Shams University · Updated on 2025-06-18
30
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries under spinal anesthesia. The study compares ketamine with placebo (normal saline) in terms of blood pressure stability and incidence of hypotensive episodes following spinal anesthesia.
CONDITIONS
Official Title
Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients American Society of Anesthesiologists Physical Status (ASA) I to II undergoing orthopedic surgeries under spinal anesthesia.
- Both Sexes.
- Patients aged equal to or above 18 years.
- Body mass index <35 kg/m2
- Duration of operation from 1 hour to 3 hours
You will not qualify if you...
- Patients' refusal of procedure or participation in the study.
- Patients with contraindication to spinal anesthesia.
- Patients with cardiovascular or pulmonary disease.
- Patients with pre-procedural hypotension (systolic arterial pressure less than 90 mmHg and/or mean arterial pressure less than 60 mmHg).
- Patients aged below 18 years.
- Duration of operation below 1 hour or above 3 hours.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ain Shams University Hospitals
Cairo, Egypt
Actively Recruiting
Research Team
A
Amira G Abdelmoniem Abdalla, M.B.B.Ch.
CONTACT
M
Mohammed S Shorbagy, M.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here