Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
All Genders
Healthy Volunteers
NCT07063732

Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

Led by McMaster University · Updated on 2025-07-14

14

Participants Needed

2

Research Sites

13 weeks

Total Duration

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AI-Summary

What this Trial Is About

The purpose of this trial is to investigate the effect of acute ketone monoester ingestion (0.6 g KME/kg body weight) on the occurrence of the ventilatory threshold and the subsequent response of blood velocity in cerebral arteries during a maximal exercise test at low altitude and high altitude.

CONDITIONS

Official Title

Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

Who Can Participate

Age: 18Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Must be a member of the research expedition team travelling to the Barcroft Research Station in White Mountain California
Not Eligible

You will not qualify if you...

  • Body mass index greater than 30
  • Use of prescribed medications (oral contraceptives allowed)
  • History of smoking
  • Current ketogenic diet or use of exogenous ketogenic supplements
  • History of heart, lung, blood vessel, or kidney disease
  • Currently pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Barcroft Research Station

Bishop, California, United States, 93514

Actively Recruiting

2

University of Guelph

Guelph, Ontario, Canada, N1G 2W1

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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