Actively Recruiting
Ketorolac in Upper Extremity Tendinopathy and Arthropathy
Led by Emory University · Updated on 2025-08-24
160
Participants Needed
4
Research Sites
230 weeks
Total Duration
On this page
Sponsors
E
Emory University
Lead Sponsor
A
American Association for Hand Surgery: AAHS
Collaborating Sponsor
AI-Summary
What this Trial Is About
Osteoarthritis (OA) and inflammatory conditions of the tendons and joints of the shoulder, elbow, hand, and wrist are common yet disabling diseases. Standard management utilizes conservative measures to minimize pain and improve function. Conservative pharmacological management commonly includes corticosteroid and ketorolac injections which have been well investigated as a modality of pain control and improved function in large joint OA. However, fewer studies yielding mixed results on the duration of symptomatic relief exist for arthropathy and tendinopathy of these joints. The goal of this study is to evaluate the efficacy of ketorolac and triamcinolone injections for common shoulder, elbow, wrist, and hand tendinopathy or arthropathy. Participants will be blinded to the treatment received. The duration of an individual participant's participation in this study is 24 weeks. During this time period, patients will be asked to return to the clinic for an in-person follow-up 6 weeks after the injection with either ketorolac or triamcinolone) in order to assess participants' outcomes. All work related to this project will take place at the Emory Sports Medicine Complex, Emory Executive Park, Emory Musculoskeletal Institute, the Emory University Orthopaedic and Spine Hospital, and the Emory Saint Joseph's Hospital. This study will add to existing knowledge by providing further insight into how wrist arthropathy should be most optimally and conservatively managed.
CONDITIONS
Official Title
Ketorolac in Upper Extremity Tendinopathy and Arthropathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older
- Symptomatic tendinopathy or arthropathy of the shoulder, elbow, hand, or wrist
- No prior surgical treatment for the affected condition
- Diagnosed with conditions such as trigger finger, De Quervain's tenosynovitis, radiocarpal osteoarthritis, first carpometacarpal joint osteoarthritis, metacarpophalangeal joint osteoarthritis, or proximal interphalangeal joint osteoarthritis
You will not qualify if you...
- Under 18 years of age
- Prior triamcinolone or ketorolac injections within the last 6 months
- Prior surgical treatment for hand condition
- Allergy or contraindication to triamcinolone or ketorolac injections
- Active infection at the treatment site, including cellulitis, purulence, fever, chills, or elevated inflammatory markers such as white blood cells, erythrocyte sedimentation rate, or C-reactive protein
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 4 locations
1
Emory Saint Joseph's Hospital
Atlanta, Georgia, United States, 30308
Actively Recruiting
2
Emory University Orthopaedic and Spine Center
Atlanta, Georgia, United States, 30324
Actively Recruiting
3
12 Executive Park Drive
Atlanta, Georgia, United States, 30329
Actively Recruiting
4
Emory University Orthopaedic and Spine Hospital
Atlanta, Georgia, United States, 30329
Actively Recruiting
Research Team
P
Paul A. Ghareeb, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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