Actively Recruiting

Phase Not Applicable
Age: 16Years +
All Genders
NCT06608706

The Key to Integrated Trauma Treatment in Psychosis Trial

Led by Haukeland University Hospital · Updated on 2026-04-24

187

Participants Needed

11

Research Sites

226 weeks

Total Duration

On this page

Sponsors

H

Haukeland University Hospital

Lead Sponsor

H

Helgeland Hospital Trust

Collaborating Sponsor

AI-Summary

What this Trial Is About

Schizophrenia spectrum disorders (SSDs) have a significant trauma etiology: trauma has been reported in 65 - 80% in this patient group and have a negative impact on prognosis. Trauma treatment is currently not offered in SSDs due to a lack of evidence. KIT is a pragmatic trial comparing the effectiveness of added trauma focused therapy, Eye Movement Desensitization and Reprocessing (EMDR) to standard treatment in SSDs. The study will compare EMDR as add on to treatment as usual (TAU) to TAU in patients with schizophrenia spectrum disorders (SSDs). The overall aim is to examine the effectiveness of EMDR on trauma symptoms in SSDs. Participants will receive max. 26 sessions of EMDR, and complete assessments before, during and after the course of therapy, in addition to a period of time (6 months) after therapy to examine long-term effects.

CONDITIONS

Official Title

The Key to Integrated Trauma Treatment in Psychosis Trial

Who Can Participate

Age: 16Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 16 years or older
  • Diagnosis of schizophrenia spectrum disorder (ICD-10 codes F20-29) confirmed by SCID 5 CV
  • Experienced trauma more than one month before assessment
  • Currently distressed by trauma with a score of 5 or higher on item 21c of the Trauma and Life Events Checklist
  • Able and motivated to participate in trauma-focused therapy
  • Able to understand and provide informed consent for treatment and study participation
Not Eligible

You will not qualify if you...

  • Primary diagnosis of substance use or alcohol dependence
  • Unable to understand spoken Norwegian
  • Presence of organic psychosis or neurological disorder
  • Acute psychosis defined by hospitalization, major medication changes, or mental health crises within the last 6 weeks
  • Current or past 6 months trauma-focused therapy

AI-Screening

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Trial Site Locations

Total: 11 locations

1

Haukeland University Hospital

Bergen, Norway, 5009

Actively Recruiting

2

Betanien DPS

Bergen, Norway

Actively Recruiting

3

Solli DPS

Bergen, Norway

Actively Recruiting

4

Voss DPS Bjørkeli

Bergen, Norway

Actively Recruiting

5

Helse Fonna HF

Haugesund, Norway

Actively Recruiting

6

Diakonhjemmet Hospital

Oslo, Norway

Actively Recruiting

7

Oslo University Hospital

Oslo, Norway

Actively Recruiting

8

Helgeland Hospital HF

Sandnessjøen, Norway, 8800

Actively Recruiting

9

Stavanger University Hospital

Stavanger, Norway

Actively Recruiting

10

UNN

Tromsø, Norway

Actively Recruiting

11

St. Olav Hospital

Trondheim, Norway

Actively Recruiting

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Research Team

E

Else-Marie Løberg, PhD, Professor

CONTACT

N

Nina Mørkved, PhD, Assoc. Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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