Actively Recruiting

Phase Not Applicable
Age: 25Years - 49Years
FEMALE
NCT06515301

Key Interventions to Improve the Follow-up Adherence Post Cervical Precancerous Lesion Treatment in Ethiopia

Led by Addis Ababa University · Updated on 2025-06-10

466

Participants Needed

1

Research Sites

57 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this pragmatic randomized control trial is to evaluate the effectiveness of three interventions in improving follow-up adherence among women treated for suspicious cervical lesions in primary healthcare settings in Ethiopia. The interventions include structured nurse-led telephone call reminders, home-visit reminders led by health extension workers, and application-based automated SMS text reminders. The main questions it aims to answer are: * Does structured nurse-led telephone call reminders improve follow-up adherence among women treated for suspicious cervical lesions compared to standard care? * Does home-reminder visits led by a Health Extension Worker (HEW) improve follow-up adherence among women treated for suspicious cervical lesions compared to standard care? * Does app-based automated SMS reminders improve follow-up adherence among women treated for suspicious cervical lesions compared to standard care? Structured Nurse-Led Telephone Call Reminders * Participants will receive proactive phone call reminders for scheduled follow-up visits. * The intervention includes three rounds: initially at 4 months post-recruitment, then every 4 months for HIV-negative women over a year, and every 2 months for 6 months for women living with HIV. Home-Reminder Visits Led by HEW Health Extension Workers (HEWs) will conduct door-to-door visits to remind participants of their scheduled follow-up appointments. • Door-to-door Visits will occur initially at 4 months (for HIV-negative women) and 2 months (for HIV-positive women) post-recruitment, then every 2 months for 6 months for HIV-positive and every 4 months for 12 months for HIV-negative participants. App-Based Automated SMS Reminders * Participants will receive SMS-based reminders for their follow-up visits. * The intervention consists of three rounds: initial texts at 4 months and 2 months post-recruitment for HIV-negative and HIV-positive women, respectively, followed by reminders every 2 months for 6 months for HIV-positive women and every 4 months for 12 months for HIV-negative women.

CONDITIONS

Official Title

Key Interventions to Improve the Follow-up Adherence Post Cervical Precancerous Lesion Treatment in Ethiopia

Who Can Participate

Age: 25Years - 49Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 30 to 49 years (HIV-negative).
  • Women aged over 25 years (HIV-positive).
  • Treated for suspicious cervical lesions after a positive VIA screening.
Not Eligible

You will not qualify if you...

  • History of hysterectomy.
  • Diagnosis of other histological invasive cervical cancer.
  • Suspicious cervical cancer cases.
  • Pregnancy.
  • Prior screening history.
  • Vaginal bleeding.
  • Lack of consent.

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Trial Site Locations

Total: 1 location

1

Worabe Health Center

Silte, Southern Ethiopia, Ethiopia

Actively Recruiting

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Research Team

M

Mr.Alemnew Destaw Mezgebu, MPH

CONTACT

D

Dr.Muluken Gizaw Turago, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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