Actively Recruiting

Age: 18Years +
FEMALE
NCT06067867

Kidney and Pregnancy Registry

Led by Brugmann University Hospital · Updated on 2023-10-05

600

Participants Needed

1

Research Sites

1055 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Maternal physiological adaptation to pregnancy plays an important role in the smooth progress of the pregnancy and the healthy growth of the fetus. This physiological adaptation takes place at the level of several organs, including the kidney. Physiological changes during a normal pregnancy take place at the anatomical, glomerular and tubular level. In the event of pre-existing kidney damage (glomerular and tubular diseases, stone disease, high blood pressure (hypertension) etc...) these adaptations will not be optimal. This will have implications for: * the course of the pregnancy with the occurrence of feto-maternal complications: miscarriages, pre-eclampsia, intrauterine growth retardation (IUGR), low birth weight, prematurity. The risk of feto-maternal complications increases with the degree of renal failure or with certain pathologies such as lupus. * progression of kidney disease Some maternal complications have long-term implications: preeclampsia is associated with a high risk of subsequent cardiovascular and renal complications. Pregnancies in these patients are high-risk pregnancies and require specialized management by an experienced group of gynecologists and nephrologists. The creation of a retrospective and prospective register by collecting demographic, clinical, biological, radiological and genetic data concerning patients at each consultation within the CHU Brugmann Hospital will allow: * to establish the epidemiological and clinico-biological characteristics of the patients followed at the Kidney and Pregnancy Clinic at the CHU Brugmann Hospital * to analyze the risk factors for feto-maternal complications * to analyze the risk factors for the occurrence of subsequent cardio-renal pathologies in patients who have had preeclampsia or an event during their pregnancy * to identify patients who will need specialized genetic testing

CONDITIONS

Official Title

Kidney and Pregnancy Registry

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Woman of childbearing age with renal damage (glomerular, tubular disease, renal lithiasis, systemic disease, metabolic diseases, congenital diseases, etc.)
  • Woman of childbearing age with hematological disorders (sickle cell disease)
  • Woman of childbearing age with kidney transplantation
  • Woman of childbearing age with high blood pressure (hypertension)
  • Woman of childbearing age undergoing pre-kidney transplant assessment for contraception and pregnancy planning
  • Woman of childbearing age with preeclampsia
  • Woman of childbearing age with multiple miscarriages
  • Woman of childbearing age with intrauterine growth retardation (IUGR) or low birth weight in fetus
  • Woman of childbearing age with family history of kidney disease
  • Pregnant women with pre-existing kidney damage
  • Pregnant women with de novo renal failure
  • Pregnant women with proteinuria
  • Pregnant women with hematuria
  • Pregnant women with chronic hypertension
  • Pregnant women with pregnancy hypertension
  • Pregnant women with renal lithiasis
  • Postpartum women with early or late pre-eclampsia
  • Postpartum women with eclampsia or HELLP syndrome
  • Postpartum women with pregnancy hypertension
  • Postpartum women with postpartum hemorrhage
  • Postpartum women with de novo renal failure postpartum
Not Eligible

You will not qualify if you...

  • Male patients
  • Menopausal patients

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

CHU Brugmann

Brussels, Belgium, 1020

Actively Recruiting

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Research Team

C

Christelle Fosso

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Kidney and Pregnancy Registry | DecenTrialz