Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
NCT07446296

Kidney Transplant Improvement Through New Exercise Training to Increase Capacity

Led by University of Pennsylvania · Updated on 2026-05-06

60

Participants Needed

1

Research Sites

109 weeks

Total Duration

On this page

Sponsors

U

University of Pennsylvania

Lead Sponsor

N

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant. The study will also learn how acceptable and useful this program is for participants. The main questions it aims to answer are: * Can a remote exercise program be delivered successfully to people on the kidney transplant waiting list? * Do participants follow the exercise program and wear a physical activity tracker as asked? * Is the program safe and well tolerated? Researchers will compare two groups to see if the exercise program leads to higher physical activity and better physical function: * Usual pre-transplant care with a physical activity tracker * Usual pre-transplant care plus an online exercise program Participants will: * Wear a wrist activity tracker to measure daily physical activity * Complete a one-week baseline period before being assigned to a study group * Be randomly assigned (like flipping a coin) to one of two groups * If assigned to the exercise group, take part in online exercise classes at home for 12 weeks with reminders and feedback, and then another 12 weeks without reminders and feedback * Answer questionnaires about their health, activity, and experience in the study This study may help researchers learn how to better support people waiting for kidney transplant through safe, home-based exercise programs.

CONDITIONS

Official Title

Kidney Transplant Improvement Through New Exercise Training to Increase Capacity

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be at least 60 years old
  • Receive transplant care at Penn Medicine
  • Be on the kidney transplant waiting list
  • Speak and understand English
  • Be able to walk
  • Have at least one physical function limitation or one frailty metric
  • Have access to a device with internet and app capability
  • Be able to provide written informed consent
  • Be cleared for physical activity by the PAR-Q or written medical clearance
Not Eligible

You will not qualify if you...

  • Had a myocardial infarction or stroke within 3 months before enrollment
  • Unable to self-monitor with study devices (e.g., due to dementia)
  • Not cleared to exercise by PAR-Q or lack written medical clearance
  • Currently participating in another physical activity study
  • Have any reason they expect they cannot complete the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Perelman Center for Advanced Medicine

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

S

Sarah Schrauben, MD, MSCE

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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