Actively Recruiting
Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease
Led by VA Office of Research and Development · Updated on 2025-11-03
100
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
Sponsors
V
VA Office of Research and Development
Lead Sponsor
U
University of Minnesota
Collaborating Sponsor
AI-Summary
What this Trial Is About
Balance problems and falls are among the most common complaints in Veterans with Parkinson's Disease (PD), but there are no effective treatments and the ability to measure balance and falls remains quite poor. This study uses wearable sensors to measure balance and uses deep brain stimulation electrodes to measure electric signals from the brain in Veterans with PD. The investigators hope to use this data to better understand the brain pathways underlying balance problems in PD so that new treatments to improve balance and reduce falls in Veterans with PD can be designed.
CONDITIONS
Official Title
Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Veterans with a clinical diagnosis of Parkinson's disease in Hoehn and Yahr stage 2-3
- Ability to give informed consent as measured by a score of 14.5 or higher on the University of California, San Diego Brief Assessment of Capacity to Consent
- Veterans with an implanted subthalamic nucleus deep brain stimulation lead and a Percept device (for Aim 3 participants)
You will not qualify if you...
- Veterans with dementia severe enough to impair healthcare decision-making
- Veterans with other forms of parkinsonism such as PSP or CBGD
- Veterans beyond Hoehn and Yahr stage 3
- Veterans with symptomatic orthostatic hypotension defined by a specific drop in blood pressure within 3 minutes of standing
- Veterans with deep brain stimulation leads implanted in locations other than the subthalamic nucleus (for Aim 3 participants)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Minneapolis VA Health Care System, Minneapolis, MN
Minneapolis, Minnesota, United States, 55417-2309
Actively Recruiting
Research Team
R
Robert A McGovern
CONTACT
N
Nicole Walker, MS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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