Actively Recruiting
Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities
Led by Erbil Polytechnic University · Updated on 2026-04-24
100
Participants Needed
1
Research Sites
39 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis. Knee osteoarthritis is a common condition, especially in older adults, causing pain, stiffness, reduced movement, and difficulty performing daily activities. Current treatments focus on reducing pain and improving joint function. In this study, 100 patients with knee osteoarthritis will be divided into two groups. One group will receive HILT combined with therapeutic exercises, while the other group will receive conventional physical therapy modalities along with the same exercises. The treatment outcomes will be evaluated over time. The main outcomes include pain reduction (measured by pain scales such as WOMAC and VAS), improvement in joint function, and structural changes in the knee assessed by MRI. In addition, laboratory tests will be used to measure inflammation, cartilage health markers, and oxidative stress before and after treatment. The goal is to determine whether HILT provides better pain relief, improves joint function, and is safe compared to standard therapy. The results may help improve rehabilitation strategies for patients with knee osteoarthritis.
CONDITIONS
Official Title
Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged between 40 and 75 years
- Clinical and radiographic diagnosis of knee osteoarthritis according to American College of Rheumatology criteria
- Kellgren-Lawrence grade 1 to 3 (mild to moderate osteoarthritis)
- Willingness to provide informed consent and comply with study procedures
You will not qualify if you...
- Active malignancy
- History of epilepsy
- Photosensitivity disorders
- Active infection in the treatment area
- Knee surgery within the past 6 months
- Scheduled knee surgery during the study period
- Kellgren-Lawrence grade 4 (severe osteoarthritis requiring surgery)
- Pregnancy or lactation
- Uncontrolled diabetes
- Severe cardiovascular disease
- Neurological disorders affecting participation or treatment outcomes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Aylan Center
Erbil, Erbil Governorate, Iraq, 44001
Actively Recruiting
Research Team
M
Mahdi Qadir, PhD
CONTACT
S
Shukur Smail, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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