Actively Recruiting

Phase Not Applicable
Age: 30Years - 60Years
All Genders
Healthy Volunteers
NCT07551245

Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities

Led by Erbil Polytechnic University · Updated on 2026-04-24

100

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis. Knee osteoarthritis is a common condition, especially in older adults, causing pain, stiffness, reduced movement, and difficulty performing daily activities. Current treatments focus on reducing pain and improving joint function. In this study, 100 patients with knee osteoarthritis will be divided into two groups. One group will receive HILT combined with therapeutic exercises, while the other group will receive conventional physical therapy modalities along with the same exercises. The treatment outcomes will be evaluated over time. The main outcomes include pain reduction (measured by pain scales such as WOMAC and VAS), improvement in joint function, and structural changes in the knee assessed by MRI. In addition, laboratory tests will be used to measure inflammation, cartilage health markers, and oxidative stress before and after treatment. The goal is to determine whether HILT provides better pain relief, improves joint function, and is safe compared to standard therapy. The results may help improve rehabilitation strategies for patients with knee osteoarthritis.

CONDITIONS

Official Title

Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities

Who Can Participate

Age: 30Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged between 40 and 75 years
  • Clinical and radiographic diagnosis of knee osteoarthritis according to American College of Rheumatology criteria
  • Kellgren-Lawrence grade 1 to 3 (mild to moderate osteoarthritis)
  • Willingness to provide informed consent and comply with study procedures
Not Eligible

You will not qualify if you...

  • Active malignancy
  • History of epilepsy
  • Photosensitivity disorders
  • Active infection in the treatment area
  • Knee surgery within the past 6 months
  • Scheduled knee surgery during the study period
  • Kellgren-Lawrence grade 4 (severe osteoarthritis requiring surgery)
  • Pregnancy or lactation
  • Uncontrolled diabetes
  • Severe cardiovascular disease
  • Neurological disorders affecting participation or treatment outcomes

AI-Screening

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Trial Site Locations

Total: 1 location

1

Aylan Center

Erbil, Erbil Governorate, Iraq, 44001

Actively Recruiting

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Research Team

M

Mahdi Qadir, PhD

CONTACT

S

Shukur Smail, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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