Exploring the Benefits of Eccentric Training for Aging Adults With Knee Osteoarthritis

What this Trial Is About

Researchers are evaluating whether a new exercise program called eccentric overload training using a flywheel device can improve stair-climbing ability in people aged 40 to 70 with knee osteoarthritis. This study aims to see if this training, which challenges muscles during their lengthening phase, can enhance muscle structure, strength, and coordination better than usual methods. The goal is to improve stair movement safety and reduce fall risk by improving muscle quality and coordination. Participants will be divided into two groups. One group will complete an 8-week eccentric overload exercise program using a kBox flywheel device, with two to three sessions per week lasting 30 to 45 minutes. Exercises include squats, step-ups, and knee extensions to mimic stair climbing. After this, there will be an 8-week period without training for the initial group. The other group will maintain usual activity for 8 weeks, then complete the same 8-week exercise program. During the study, participants will undergo various assessments at baseline, 10 weeks, and 19 weeks. These include measures of stair-stepping smoothness, muscle health via ultrasound, strength tests, stair walking time, physical performance scores, joint movement analyses, and self-reported pain. The study will monitor how these outcomes change with training and detraining to understand the effects on muscle and movement in knee osteoarthritis.

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