Actively Recruiting
KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II
Led by Seoul National University Bundang Hospital · Updated on 2025-04-27
1000
Participants Needed
32
Research Sites
230 weeks
Total Duration
On this page
Sponsors
S
Seoul National University Bundang Hospital
Lead Sponsor
K
Korean Cancer Study Group
Collaborating Sponsor
AI-Summary
What this Trial Is About
A national, prospective, multi-center, open-label, multi-cohort study comprised of a framework to screen patients for actionable targets and evaluation of molecular profiling guided therapy recommended by MTB based on genomic alterations using targeted and/or immunotherapies outside of the approved indications via local clinical practice (Tier 1 \& 2) and clinical trials (Tier 3)
CONDITIONS
Official Title
KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 19 years of age or older
- Histologically proven locally advanced or metastatic solid tumors with disease progression on standard first line anti-cancer treatment and/or no standard treatment option
- Genomic test results available from an MFDS-accredited laboratory, clinical trial/study, or other regulatory-approved labs
- Ability to understand and sign informed consent
- Life expectancy of at least 12 weeks
- Adequate recovery from most recent systemic or local cancer treatment
You will not qualify if you...
- Receiving any anti-cancer treatment within 2 weeks prior to study treatment
- Any clinical condition making molecular profiling guided therapy unsuitable as judged by site physicians
- Ongoing toxicities of grade 2 or higher related to previous treatment except peripheral neuropathy; peripheral neuropathy of grade 3 or higher excluded
- Pregnant, breastfeeding, or intending to become pregnant during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 32 locations
1
Soonchunhyang University Hospital Bucheon
Bucheon-si, South Korea
Actively Recruiting
2
Chungbuk National University Hospital
Chungju, South Korea
Actively Recruiting
3
Keimyung University Dongsan Hospital
Daegu, South Korea
Actively Recruiting
4
Kyungpook National University Chilgok Hospital
Daegu, South Korea
Actively Recruiting
5
Yeungnam University Medical Center
Daegu, South Korea
Actively Recruiting
6
Chungnam National University Hospital
Daejeon, South Korea
Actively Recruiting
7
National Cancer Center
Goyang, South Korea
Actively Recruiting
8
Chonnam National University Hwasun Hospital
Hwasun, South Korea
Actively Recruiting
9
Gachon University Gil Medical Center
Incheon, South Korea
Actively Recruiting
10
The Catholic University of Korea, Incheon St. Mary's Hospital
Incheon, South Korea
Actively Recruiting
11
Jeonbuk National University Hospital
Jeonju, South Korea
Actively Recruiting
12
Gyeongsang National University Hospital
Jinju, South Korea
Actively Recruiting
13
Dong-A University Hospital
Pusan, South Korea
Actively Recruiting
14
Cha University Bundang Medical Center
Seongnam, South Korea
Actively Recruiting
15
Seoul National University Bundang Hospital
Seongnam, South Korea
Actively Recruiting
16
Asan Medical Center
Seoul, South Korea
Actively Recruiting
17
Chung-ang University Hospital
Seoul, South Korea
Actively Recruiting
18
Ewha womans university Mokdong Hospital
Seoul, South Korea
Actively Recruiting
19
Gangbuk Samsung Hospital
Seoul, South Korea
Actively Recruiting
20
Hanyang University Hospital
Seoul, South Korea
Terminated
21
Korea University Anam Hospital
Seoul, South Korea
Actively Recruiting
22
Korea University Guro Hospital
Seoul, South Korea
Actively Recruiting
23
Samsung Medical Center
Seoul, South Korea
Actively Recruiting
24
Seoul National University Hospital
Seoul, South Korea
Actively Recruiting
25
The Catholic University of Korea, Seoul ST. Mary's Hospital
Seoul, South Korea
Actively Recruiting
26
The Catholic University of Korea, Yeouido St. Mary's Hospital
Seoul, South Korea
Actively Recruiting
27
Yonsei Cancer Hospital
Seoul, South Korea
Actively Recruiting
28
Ajou University Hospital
Suwon, South Korea
Actively Recruiting
29
The Catholic University of Korea, ST. Vincent's Hospital
Suwon, South Korea
Actively Recruiting
30
Ulsan University Hospital
Ulsan, South Korea
Actively Recruiting
31
Wonju Severance Christian Hospital
Wŏnju, South Korea
Actively Recruiting
32
Pusan National University Yangsan Hospital
Yangsan, South Korea
Actively Recruiting
Research Team
J
JEEHYUN KIM
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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