Actively Recruiting

Phase Not Applicable
Age: 65Years - 90Years
All Genders
Healthy Volunteers
NCT06296875

The Krill Ageing Muscle Mechanisms (KAMM) Study

Led by University of Glasgow · Updated on 2026-05-01

80

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to determine the mechanisms via which krill oil supplementation increases muscle strength and whether this translates to improvements in gait and functional characteristics in older adults. The studies we will carry out will establish, in healthy older adults, the effects of 6 months of supplementation with krill oil Objective 1) Muscle structure and function Hypothesis: Krill oil supplementation will increase muscle size and strength alongside positive changes in muscle architecture (pennation angle and fascicle length). Objective 2) Neuromuscular control and central nervous system (CNS) function Hypothesis: Krill oil supplementation will improve Neuromuscular Junction (NMJ) transmission stability and increase central drive and intramuscular coherence, as a measure of muscle synergy. Objective 3) Gait and functional characteristics Hypothesis: Krill oil supplementation will improve gait and functional characteristics.

CONDITIONS

Official Title

The Krill Ageing Muscle Mechanisms (KAMM) Study

Who Can Participate

Age: 65Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Body mass index (BMI) less than or equal to 30 kg/m2
  • Age 65 years or older
  • Ability to provide consent
  • Living within the Glasgow area
Not Eligible

You will not qualify if you...

  • Diabetes mellitus
  • Severe cardiovascular disease
  • Seizure disorders
  • Uncontrolled hypertension (greater than 150/90 mmHg)
  • Active cancer or cancer remission less than 5 years
  • Participation in resistance exercise training within the last 6 months
  • Impairments limiting muscle function assessments
  • Dementia
  • Fish or shellfish allergy
  • Taking medications affecting muscle (e.g., steroids, SSRIs) or anticoagulants (e.g., warfarin)
  • Taking omega-3 supplements in the last 3 months
  • Regularly consuming one or more portions of oily fish per week
  • Unable to understand English

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Glasgow

Glasgow, United Kingdom

Actively Recruiting

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Research Team

S

Stuart Gray

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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