Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
All Genders
Healthy Volunteers
NCT07433920

L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted Computer-Guided Socket Shield Immediate Implantation

Led by Kafrelsheikh University · Updated on 2026-03-18

45

Participants Needed

2

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

the rationale of the current study is to address a focused and clinically relevant gap in socket shield therapy: which biologic modality best supports healing of the shield-implant gap when SST is performed under a standardized, digitally guided workflow. The study will compare three shield-implant gap filling modalities: (i) L-PRF alone (without membrane), (ii) sticky tooth (autogenous dentin graft +i- PRF), and (iii) sticky bone (particulate graft + i- PRF) under AI-assisted, patient-specific guided implant placement based on IOS/CBCT superimposition, with CBCT follow-up at immediate, 3 months, and 6 months. The working hypothesis is that biologically active, cohesive composites (sticky tooth and sticky bone) will provide superior hard- and soft-tissue dimensional stability compared with PRF alone by improving space maintenance and early wound stability in the shield-implant gap . The null hypothesis is that there will be no statistically significant differences between the three modalities in radiographic and digitally assessed clinical outcomes over the 6-month follow-up period .

CONDITIONS

Official Title

L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted Computer-Guided Socket Shield Immediate Implantation

Who Can Participate

Age: 18Years - 45Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Medically healthy patients classified as ASA I or ASA II
  • Age greater than 18 years
  • Presence of one non-restorable hopeless anterior tooth due to extensive caries, cervical/root fracture, vertical or oblique root fracture, multiple failed endodontic treatments, or root resorption
  • Sufficient apical or palatal bone to achieve primary implant stability
Not Eligible

You will not qualify if you...

  • Patients classified as ASA III, ASA IV, or ASA V
  • Vertical root fracture involving the labial aspect of the root planned to be retained as the facial shield
  • Horizontal root fracture located too far apically
  • Presence of acute (active) periapical infection
  • Large chronic periapical lesion
  • Insufficient bone apical to the extraction socket to achieve primary stability
  • Ankylosed tooth positioned too apically relative to adjacent teeth

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

faculty of dentistry, kafrelsheikh University

Kafr ash Shaykh, Kafrelsheikh, Egypt, 214312

Actively Recruiting

2

Walid Elamrousy

Kafr ash Shaykh, Egypt, 76130

Actively Recruiting

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Research Team

W

Walid Elamrousy, PhD

CONTACT

N

Nour Hatata, Phd

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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