Actively Recruiting
L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted Computer-Guided Socket Shield Immediate Dental Implantation
Led by Kafrelsheikh University · Updated on 2026-03-18
45
Participants Needed
2
Research Sites
3 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating which biological material best supports healing in the gap between the implant and the shield during socket shield therapy (SST). This study focuses on comparing three methods: leukocyte-platelet rich fibrin (L-PRF) alone, sticky tooth (autogenous dentin graft with injectable PRF), and sticky bone (particulate graft with injectable PRF). The study uses an AI-assisted, computer-guided implant placement approach and follows patients with CBCT scans immediately, at 3 months, and at 6 months to assess healing and tissue stability. The treatments involve preparing the implant site with socket shield technique and then filling the gap using one of the three grafting materials. L-PRF is gently packed into the gap after implant placement. The sticky tooth group uses dentin particles made from the extracted root mixed with PRF clot to fill the gap. The sticky bone group uses xenograft particles combined with PRF clot for the gap filling. The study uses advanced imaging and digital workflows to ensure precise implant placement and standardized treatment. Participants will undergo implant placement with socket shield technique followed by one of the three grafting methods. They will have follow-up CBCT imaging at baseline, 3 months, and 6 months to monitor bone and tissue changes. The study measures outcomes such as marginal bone level and peri-implant vertical bone defect depth over 12 months. The research team monitors healing progress, tissue stability, and hard-tissue dimensional changes during this period, with total participation lasting up to one year after treatment.
CONDITIONS
Brief Title
L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted Computer-Guided Socket Shield Immediate Implantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Medically healthy patients classified as ASA I or ASA II
- Age between 18 and 45 years
- Presence of one non-restorable hopeless anterior tooth due to extensive caries, cervical/root fracture, vertical or oblique root fracture, multiple failed endodontic treatments, or root resorption
- Sufficient apical or palatal bone to obtain primary implant stability
You will not qualify if you...
- Patients classified as ASA III, ASA IV, or ASA V
- Vertical root fracture involving the labial aspect of the root planned to be retained as the facial shield
- Horizontal root fracture that is too far apically located
- Presence of acute (active) periapical infection
- Large chronic periapical lesion
- Lack of sufficient bone apical to the extraction socket for primary stability
- Ankylosed tooth positioned too apically in relation to adjacent teeth
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single procedure at implantation
Participants receive immediate dental implant placement with the socket shield technique. The implant-shield gap is grafted using either PRF alone, sticky tooth graft, or sticky bone graft depending on the assigned group.
1 surgical visit (in-person)
Duration - 12 months
Participants are monitored to assess bone level and peri-implant bone defect depth over 12 months following implantation.
Multiple follow-up visits over 12 months
Trial Site Locations
Total: 2 locations
1
faculty of dentistry, kafrelsheikh University
Kafr ash Shaykh, Kafrelsheikh, Egypt, 214312
Actively Recruiting
2
Walid Elamrousy
Kafr ash Shaykh, Egypt, 76130
Actively Recruiting
Research Team
W
Walid Elamrousy, PhD
N
Nour Hatata, Phd
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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