Actively Recruiting

Phase 4
Age: 19Years +
FEMALE
NCT05309460

Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial

Led by Nebraska Methodist Health System · Updated on 2024-04-12

600

Participants Needed

1

Research Sites

127 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Randomized trial comparing risk of hospital readmission and hypertensive complications between patients managed on Labetalol compared to Nifedipine.

CONDITIONS

Official Title

Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial

Who Can Participate

Age: 19Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients admitted for delivery by cesarean or vaginal delivery at 24 weeks gestation or greater with hypertension
  • Hypertension defined as systolic blood pressure 6140 mmHg or diastolic blood pressure 690 mmHg on two occasions at least 4 hours apart
  • Hypertension diagnosed according to ACOG definition for pregnancy-related hypertension
  • Treatment escalation after enrollment to achieve normal blood pressure
Not Eligible

You will not qualify if you...

  • History of moderate persistent asthma, coronary artery disease, heart failure, AV heart block, or pulmonary edema
  • Contraindication to either Nifedipine or Labetalol
  • Heart rate less than 60 or greater than 110 beats per minute
  • Native language other than English or Spanish

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Nebraska Methodist Women's Hospital

Omaha, Nebraska, United States, 68022

Actively Recruiting

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Research Team

T

Todd Lovgren, MD

CONTACT

J

Joshua Dahlke, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial | DecenTrialz