Actively Recruiting

Phase Not Applicable
Age: 21Years - 70Years
FEMALE
NCT04929769

Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IB1,IB2,IIA1)

Led by Obstetrics & Gynecology Hospital of Fudan University · Updated on 2021-11-01

780

Participants Needed

1

Research Sites

278 weeks

Total Duration

On this page

Sponsors

O

Obstetrics & Gynecology Hospital of Fudan University

Lead Sponsor

C

Children's Hospital of Fudan University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to confirm whether there is a difference between laparoscopic radical hysterectomy (LRH) and abdominal radical hysterectomy (ARH) in patient survival for Cervical Cancer (Stage IB1, IB2, IIA1).

CONDITIONS

Official Title

Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IB1,IB2,IIA1)

Who Can Participate

Age: 21Years - 70Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of squamous carcinoma of the cervix, adenocarcinoma, or squamous adenocarcinoma at stage IB1, IB2, or IIA1
  • Age 21 years or older and 70 years or younger
  • Eligible for surgery type B or C according to Q-M surgical staging
  • Normal liver and kidney function and blood count within specified ranges (Hemoglobin > 60g/L, Platelets > 70×10^9/L, Leukocytes > 3×10^9/L, Creatinine < 50mg/dL, Transaminase levels no more than 3 times the normal maximum)
  • No history of other cancers
  • Not pregnant
  • Karnofsky performance score 60 or higher
  • Voluntarily consented and willing to comply with follow-up
  • No psychiatric or serious immune system disorders such as lupus erythematosus, myasthenia gravis, or HIV infection
Not Eligible

You will not qualify if you...

  • Unable to undergo surgery due to contraindications
  • Previous pelvic or abdominal radiotherapy or neoadjuvant chemotherapy for cervical cancer
  • Recurrent cervical cancer
  • Imaging (CT, MRI, or PET-CT) suggesting suspicious pelvic lymph node metastasis larger than 2cm

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Obstetrics and Gynecology Hospital of Fudan University

Shanghai, Shanghai Municipality, China, 200000

Actively Recruiting

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Research Team

X

Xin Wu, PHD

CONTACT

J

Jiang Hua, PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IB1,IB2,IIA1) | DecenTrialz