Actively Recruiting
Laparoscopic and Endoscopic Collaborative Surgery as Rescue-treatment for Advanced Gastric Cancer
Led by Region Stockholm · Updated on 2025-07-22
20
Participants Needed
1
Research Sites
145 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The standard treatment for advanced gastric cancer without metastases is gastrectomy, where the whole stomach or a large proportion is removed surgically together with regional lymph nodes. Some patients cannot tolerate this invasive procedure because of old age or comorbidities. A tumor left in place can cause local symptoms such as bleeding or outlet obstruction. In this study, the investigators want to test the safety and feasibility of Laparoscopic and Endoscopic Collaborative Surgery (LECS) as a less invasive treatment option to locally remove gastric tumors without requiring extensive surgery in these frail patients. LECS is a minimally invasive surgical technique where the tumor margin is first marked from the inside with a gastroscope, followed by surgical removal of the lesion under endoscopic guidance.
CONDITIONS
Official Title
Laparoscopic and Endoscopic Collaborative Surgery as Rescue-treatment for Advanced Gastric Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- pT2-T4aN0M0 gastric carcinoma
- Borrmann type 1-2 less than 5 cm or Borrmann type 3 less than 2 cm
- Assessed by multidisciplinary tumor board as not fit for gastrectomy
- Signed informed consent
You will not qualify if you...
- Borrmann type 4 tumor
- Tumor located in the cardia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Karolinska University Hospital
Stockholm, Sweden, 14186
Actively Recruiting
Research Team
I
Ioannis Rouvelas, MD, PhD
CONTACT
H
Henrik Maltzman, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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