Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
FEMALE
NCT06883409

Laparoscopic Interval Cytoreductive Surgery in Advance Ovarian Cancer

Led by Instituto Nacional de Cancerologia de Mexico · Updated on 2025-03-26

33

Participants Needed

1

Research Sites

188 weeks

Total Duration

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AI-Summary

What this Trial Is About

This is a study that aims to demonstrate the non-inferiority of minimally invasive surgery versus open surgery, as an approach for patients with advanced ovarian cancer who received neoadjuvant chemotherapy, giving them the benefits of laparoscopic surgery. This way they can continue with their complementary treatment.

CONDITIONS

Official Title

Laparoscopic Interval Cytoreductive Surgery in Advance Ovarian Cancer

Who Can Participate

Age: 18Years - 80Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of epithelial ovarian cancer (all subtypes) at stage III or IV
  • Partial or complete response after 3-4 cycles of neoadjuvant chemotherapy, confirmed by PET-CT imaging
  • CA 125 blood level less than 200
  • ECOG performance status 0 to 2 without medical contraindications for surgery (ASA score 64 2 or Goldman score 64 2)
Not Eligible

You will not qualify if you...

  • Partial response with ongoing ascites or pleural effusion
  • Presence of unresectable disease including multiple intrahepatic liver metastases
  • Retroperitoneal lymph node clusters larger than 2 cm above the renal lymph nodes
  • Metastatic disease above the diaphragm
  • Multiple intestinal involvements and mesentery retraction

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Instituto Nacional de Cancerologia

México, Tlalpan, Mexico, 14080

Actively Recruiting

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Research Team

D

David Isla Ortiz, MD, M. Cs.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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