Safety and Short-term Outcomes of Laparoscopic Pancreaticoduodenectomy for Treating Pancreatic and Periampullary Cancers A Single Center Experience

What this Trial Is About

Researchers are evaluating laparoscopic pancreaticoduodenectomy LPD, a minimally invasive surgical technique used to treat pancreatic and periampullary cancers as well as other related conditions. The study aims to assess the safety, feasibility, and short-term oncological outcomes of LPD, a complex and technically demanding procedure that involves removing parts of the pancreas and surrounding structures. Although open pancreaticoduodenectomy has been the standard treatment, laparoscopic surgery is being explored as a less invasive alternative with the potential to reduce complications. The study involves performing laparoscopic pancreaticoduodenectomy using a 6-port technique with specific patient positioning and surgical steps such as vessel ligation, lymphadenectomy, and reconstruction of digestive tract connections. Surgeons use advanced tools like harmonic scalpels, Ligasure, and staplers during the procedure. This approach is applied only if no vascular invasion or metastasis is detected. The study focuses on patients with resectable pancreatic head cancer, cholangiocarcinoma, duodenal cancer, and ampullary tumors who are fit for this surgery. Participants undergo careful screening to confirm eligibility and avoid inoperable or metastatic cases. Researchers assess surgical specimens pathologically within 1 to 2 weeks after surgery and monitor outcomes including pancreatic fistula rates, operative time, blood loss, blood transfusions, length of hospital stay, and intensive care unit duration over up to 90 days. The study collects detailed data to evaluate the short-term safety and effectiveness of laparoscopic pancreaticoduodenectomy for cancer treatment.

Laparoscopic Pancreaticoduodenectomy