Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07400237

Laparoscopic Ultrasound Versus Fluorescence Cholangiography in Technically Challenging Laparoscopic Cholecystectomy

Led by Consorci Sanitari Integral · Updated on 2026-02-10

62

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

Sponsors

C

Consorci Sanitari Integral

Lead Sponsor

H

Hospital Moisés Broggi de Sant Joan Despí, Barcelona

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a multicenter, prospective, interventional clinical trial designed to evaluate and compare two intraoperative imaging modalities: laparoscopic ultrasound (LUS) and fluorescence cholangiography with indocyanine green (ICG), for the identification of biliary anatomy in technically challenging laparoscopic cholecystectomy. All enrolled subjects will undergo both LUS and ICG during the index procedure, following a standardized sequence, in order to allow intra-subject comparison. LUS will be performed first, followed by fluorescence cholangiography prior to Calot's triangle dissection. The primary endpoint is the successful identification of the critical junction. Secondary endpoints include visualization of individual biliary structures, time to visualization, total operative time, intraoperative and postoperative complications.

CONDITIONS

Official Title

Laparoscopic Ultrasound Versus Fluorescence Cholangiography in Technically Challenging Laparoscopic Cholecystectomy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 218 years or older
  • Provided written informed consent
  • Scheduled for laparoscopic cholecystectomy with expected technical difficulty due to acute cholecystitis, previous cholangitis, pancreatitis, endoscopic retrograde cholangiopancreatography, prior upper abdominal surgery, or obesity (BMI 230 kg/m�B2)
Not Eligible

You will not qualify if you...

  • Known allergy to indocyanine green (ICG) or iodine
  • Pregnancy or breastfeeding
  • High risk of choledocholithiasis according to ESGE guidelines
  • Thyroid disease
  • Suspected gallbladder cancer
  • ASA class IV or V
  • Chronic kidney disease stage higher than IIIb
  • Planned open cholecystectomy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Complex Hospitalari Universitari Moisès Broggi, Consorci Sanitari Integral

Sant Joan Despí, Barcelona, Spain, 08970

Actively Recruiting

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Research Team

A

Andrea Sanz LLorente, M.D.

CONTACT

S

Sergio González Martínez, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Laparoscopic Ultrasound Versus Fluorescence Cholangiography in Technically Challenging Laparoscopic Cholecystectomy | DecenTrialz