Actively Recruiting

Age: 65Years +
All Genders
NCT07347431

Large Language Model for Understanding and Monitoring Elderly Neurocognition

Led by Northumbria Healthcare NHS Foundation Trust · Updated on 2026-04-21

60

Participants Needed

1

Research Sites

41 weeks

Total Duration

On this page

Sponsors

N

Northumbria Healthcare NHS Foundation Trust

Lead Sponsor

N

Newcastle University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Dementia affects millions of people worldwide, and early diagnosis is essential for getting the right care and support. Doctors rely on collateral histories (accounts from family members or caregivers) to understand changes in a person's memory and thinking. However, these histories can be incomplete, unstructured, or difficult to obtain, making diagnosis more challenging. This study will test LUMEN (Large Language Model for Understanding and Monitoring Elderly Neurocognition), an AI-powered conversation tool designed to help caregivers describe their loved one's symptoms more effectively. By asking structured questions and guiding the conversation, LUMEN can create clear, well-organised reports for memory clinic doctors. This could make assessments quicker, more accurate, and less stressful for families. We will test LUMEN in real-world clinics by asking caregivers and doctors to use it and provide feedback. We want to understand how easy it is to use, whether it could improve the quality of information shared, and how it fits into existing NHS memory clinic processes. We will also run co-production workshops with community groups to ensure the tool is accessible to people from diverse cultural and language backgrounds. This research is exciting because it explores how artificial intelligence can improve dementia care. If successful, LUMEN could enhance the diagnostic process, reduce carer burden, and help more people access dementia support sooner. In the future, this tool could be used nationwide in memory clinics, improving care for thousands of families.

CONDITIONS

Official Title

Large Language Model for Understanding and Monitoring Elderly Neurocognition

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Carers of patients attending Memory Clinic appointments
  • Aged 18 or over
  • Both patients and carers can provide informed consent
  • Basic English literacy
  • Clinicians must have at least 2 years of specialist dementia care experience and be personally responsible for dementia diagnosis
  • Must provide informed consent
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

North Tyneside General Hospital is Rake Lane

North Shields, United Kingdom, NE29 8NH

Actively Recruiting

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Research Team

J

Judith R Harrison, MBChB

CONTACT

L

Lisa Gallagher

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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