Actively Recruiting
Laryngeal Cryotherapy for Refractory Neurogenic Cough
Led by University of Texas Southwestern Medical Center · Updated on 2026-01-30
28
Participants Needed
1
Research Sites
214 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate the safety and efficacy of upper aerodigestive tract cryotherapy treatment in patients with refractory neurogenic cough in a prospective pilot study with a validated patient reported outcome measure
CONDITIONS
Official Title
Laryngeal Cryotherapy for Refractory Neurogenic Cough
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients 18 years or older with diagnosis of neurogenic cough
- Neurogenic cough diagnosed after excluding other causes with persistent cough lasting 8 weeks or longer
- Negative evaluation for sinonasal allergies, chronic sinusitis, cough-variant asthma, and GERD
- Willingness to participate in a clinical trial
You will not qualify if you...
- Uncontrolled reflux with a Reflux Symptom Index score of 13 or higher
- Vocal fold abnormalities or impairment
- History of asthma or lung conditions that are not well controlled
- Uncontrolled allergic rhinitis with Total Nasal Symptom Score greater than 6
- Symptoms of postnasal drip
- Current smoking
- Use of neuromodulator medications
- Unwillingness to participate or sign informed consent
- End stage medical disease with poor life expectancy
- Medical instability preventing enrollment
- Abnormal chest X-ray results
- Abnormal pulmonary function tests
- Positive local allergy panel (combined RAST testing)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UT Southwestern Medical Center
Dallas, Texas, United States, 75235
Actively Recruiting
Research Team
S
Shumon Dhar, MD
CONTACT
P
Paula Arellano-Cruz
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here