Actively Recruiting
Laryngeal and Vocal Tract Strategies to Reduce Vocal Fold Contact Pressure
Led by University of California, Los Angeles · Updated on 2025-12-15
60
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
Sponsors
U
University of California, Los Angeles
Lead Sponsor
N
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Phonotraumatic vocal hyperfunction is one of the most frequently occurring conditions to affect the voice. This voice disorder often involves vocal fold injury due to repeated, excessive contact pressure between the vocal folds when they collide during voice production. In the clinic, voice therapy attempts to modify unhealthy vocal behaviors through different techniques or exercises. While voice therapy is generally considered effective, the scientific rationale for its therapeutic benefits still remains unclear. It is generally believed that these exercises lead to adjustments in the larynx and vocal tract that reduce vocal fold contact pressure. However, this assumption has never been tested in humans or laboratory experiments. The goal of this clinical trial is to investigate the effectiveness of voice therapy in reducing vocal fold contact pressures and in eliciting the hypothesized favorable laryngeal and vocal tract configurations.
CONDITIONS
Official Title
Laryngeal and Vocal Tract Strategies to Reduce Vocal Fold Contact Pressure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18-40 years (to minimize developmental changes associated with adolescent and elderly age)
- Diagnosis by a fellowship trained laryngologist of mid-membranous lesions that are phonotraumatic by history and appearance
- Referral for voice therapy
You will not qualify if you...
- Medical comorbidities beyond seasonal allergy and laryngopharyngeal reflux
- Vocal fold lesions less responsive to voice therapy (e.g., vocal fold cysts)
- Claustrophobia
- Inability to replicate required fundamental frequencies at determined intensity levels
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UCLA Rehab Center
Los Angeles, California, United States, 90095
Actively Recruiting
Research Team
Z
Zhaoyan Zhang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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