Actively Recruiting
Incidence, Perioperative Risk Factors, and Prognosis of Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia: A Retrospective Study
Led by Zhejiang University · Updated on 2026-01-22
1200
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying patients who had tracheal intubation under general anesthesia at a hospital in Zhejiang University between October 2015 and September 2025. The focus is on problems related to throat and voice complaints after surgery, especially hoarseness, to understand risk factors and improve care during surgery. This is an observational study using past patient data to learn about laryngopharyngeal injury and its outcomes. The study involves collecting and analyzing clinical data from patients who needed ear, nose, and throat consultations due to throat complaints like hoarseness, sore throat, cough, or choking after non-ear, nose, and throat surgeries. Researchers review medical records and anesthesia data, then follow up by phone to assess patient recovery and prognosis. The main outcome is the risk factors for hoarseness after surgery, with additional outcomes including how often hoarseness happens, its severity, vocal cord injury, and related issues. Participants are monitored using the hospital's anesthesia and electronic medical record systems, combined with telephone follow-ups to check how their symptoms develop up to 150 days after surgery. The study measures postoperative voice changes, throat injury, and specific complications like arytenoid dislocation. The goal is to help reduce throat injury during surgery and guide better anesthesia practices. Participation involves data review and phone follow-up without new treatments, lasting up to 150 days post-operation.
CONDITIONS
Brief Title
Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who underwent general anesthesia with tracheal intubation at the First Affiliated Hospital of Zhejiang University School of Medicine between October 2015 and September 2025
- Patients who required otolaryngological consultation due to postoperative laryngopharyngeal complaints such as hoarseness, sore throat, cough, or choking on drinking water
- Patients who had non-otolaryngological surgery
You will not qualify if you...
- Patients with a history of laryngopharyngeal lesions, including granuloma, polyp, tumour, or vocal cord paralysis
- Patients with a preexisting tracheotomy
- Patients requiring postoperative tracheotomy
- Patients with incomplete medical records
- Patients who had multiple surgeries but could not identify which surgery caused the laryngopharyngeal complaints
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Perioperative period up to 150 days
Participants undergo evaluation due to postoperative laryngopharyngeal complaints such as hoarseness, sore throat, cough, or choking on drinking water.
Multiple visits depending on symptom assessment
Duration - Up to 150 days postoperatively
Participants are observed to analyze perioperative risk factors and prognosis of laryngopharyngeal injury after endotracheal intubation.
Follow-up visits as needed for up to 150 days
Trial Site Locations
Total: 2 locations
1
he First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Completed
2
The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
D
Diansan Su
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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