Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
Healthy Volunteers
NCT06389071

Laser Treatment for Lichen Sclerosus

Led by Sciton · Updated on 2026-04-23

50

Participants Needed

1

Research Sites

199 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Fractional ablative laser treatment for Lichen Sclerosus lesion

CONDITIONS

Official Title

Laser Treatment for Lichen Sclerosus

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female aged 18 years or older
  • Biopsy-proven vulvar lichen sclerosus lesion
  • Experiencing one or more symptoms of lichen sclerosus such as dryness, itching, burning, bleeding, blistering, soreness, easy bruising, easy tearing, ulcerated lesions, or painful intercourse
  • Negative urine pregnancy test if of childbearing potential before enrollment
  • No vulvovaginal infection including fungi, bacterial vaginosis, or sexually transmitted infections
  • Ability to understand and sign informed consent, questionnaires, and all investigation requirements
  • Willing to consent to clinical photographs and ultrasound images of the treatment area
  • Willing and able to follow the schedule of treatments and follow-up visits
Not Eligible

You will not qualify if you...

  • Pregnant, less than 3 months postpartum, or planning to become pregnant during the study
  • Nursing mother
  • History of uncontrolled malignant disease
  • Active or chronic urogenital infection such as candida, herpes, herpes simplex, bacterial vaginosis, trichomoniasis, or other infections
  • Immunocompromised conditions including lymphoma, AIDS, Wiskott-Aldrich syndrome
  • Genital skin diseases like psoriasis due to risk of koebnerizing
  • Use of immunosuppressants like mycophenolate, retinoids, azathioprine, or cyclosporin
  • Known allergy or intolerance to local anesthesia
  • History of connective tissue disease
  • Known tendency for keloid formation
  • Medical conditions that may affect wound healing
  • Any other reason deemed by the investigator to prohibit participation in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Clinique Medicale Uro-Gyneco de l'Abitibi

Val-d'Or, Quebec, Canada, J9P1W1

Actively Recruiting

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Research Team

J

J Patel

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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