Actively Recruiting
Late Onset Alzheimer's Disease
Led by Columbia University · Updated on 2025-05-16
10000
Participants Needed
12
Research Sites
545 weeks
Total Duration
On this page
Sponsors
C
Columbia University
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to is to focus on the genetic influences on Alzheimer's Disease (AD) risk. The investigators are looking for families and/or individuals (affected or unaffected) of any ethic background (African American, Caucasian, and Hispanics) with a family history of AD and willing to participate.
CONDITIONS
Official Title
Late Onset Alzheimer's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Established diagnosis of definite or probable Alzheimer's Disease or a related neurodegenerative disorder such as Frontotemporal Dementia or Lewy Body Dementia (including sporadic cases)
- Having a living sibling with probable or possible Alzheimer's Disease
- Having a third living relative affected with Alzheimer's Disease (onset age 50 or older) or unaffected (60 or older)
- Participants in the proband's generation with an identified companion serving as an informant
- Participants who can consent or have a surrogate/proxy to provide consent
You will not qualify if you...
- Failure to identify an appropriate informant
- Uncertainty of the clinical diagnosis of Alzheimer's Disease or related disorder
- Discovery of another diagnosis that could explain the clinical symptoms
- Unwillingness to participate
- Failure to identify a living sibling with Alzheimer's Disease or related disorder (except sporadic Frontotemporal Dementia and Lewy Body Dementia cases)
- Participants lacking capacity to consent without a surrogate, proxy, or next of kin to provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 12 locations
1
University of Washington
Washington D.C., District of Columbia, United States, 98105
Actively Recruiting
2
University of Miami
Miami, Florida, United States, 33124
Actively Recruiting
3
Rush University
Aurora, Illinois, United States, 60612
Actively Recruiting
4
Indiana University
Bloomington, Indiana, United States, 47405
Actively Recruiting
5
NCRAD at Indiana University
Indianapolis, Indiana, United States, 46202
Actively Recruiting
6
Mayo Clinic
Rochester, Minnesota, United States, 55901
Actively Recruiting
7
Joanne Norton
St Louis, Missouri, United States, 63130
Actively Recruiting
8
Columbia University Irving Medical Center
New York, New York, United States, 10032
Actively Recruiting
9
North Carolina State University
Raleigh, North Carolina, United States, 27695
Actively Recruiting
10
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
11
University of Texas Southwestern
Dallas, Texas, United States, 75390
Actively Recruiting
12
University of Washington
Seattle, Washington, United States, 98195
Actively Recruiting
Research Team
D
Dolly Reyes-Dumeyer
CONTACT
A
Amanda Chan
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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