Actively Recruiting
Lateral Pelvic Lymph Node Dissection for Rectal Neuroendocrine Neoplasms Undergoing Laparoscopic Total Mesenteric Excision
Led by National Cancer Center, China · Updated on 2024-02-28
30
Participants Needed
1
Research Sites
313 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to investigate the metastatic status of lateral pelvic lymph nodes in rectal neuroendocrine neoplasms (rNENs) undergoing laparoscopic total mesenteric excision (TME). The hypothesis is that the rate of lateral lymph node metastasis is underestimated in rNENs undergoing TME, necessitating concurrent lateral Pelvic lymph node dissection.
CONDITIONS
Official Title
Lateral Pelvic Lymph Node Dissection for Rectal Neuroendocrine Neoplasms Undergoing Laparoscopic Total Mesenteric Excision
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biopsy proven rectal neuroendocrine neoplasm (neuroendocrine tumor and carcinoma)
- Preoperative imaging shows tumor maximum diameter > 2 cm, or
- Tumor maximum diameter 1-2 cm with clinical staging T2 or higher, or
- Tumor maximum diameter 1-2 cm with Grade 3 differentiation, or
- Recurrence after local excision under endoscopy
- Eastern Cooperative Oncology Group (ECOG) performance score 64 1
- Written informed consent
You will not qualify if you...
- Complete intestinal obstruction
- Hepatitis activity and peripheral neuropathy (e.g., peripheral neuritis, pseudomeningitis, motor neuritis, sensory impairment)
- Significant organ dysfunction or other significant diseases including coronary artery disease, cardiovascular disease, myocardial infarction within last 12 months, severe neurological or psychiatric history, severe infection, active disseminated intravascular coagulation
- Pregnancy or breastfeeding
- Alcohol abuse or drug addiction
- Concurrent uncontrolled medical condition
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
National Cancer Center
Beijing, Beijing Municipality, China, 100000
Actively Recruiting
Research Team
Y
Yueyang Zhang, M.D.
CONTACT
Z
Zheng Xu, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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