Actively Recruiting
Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors
Led by University of Cincinnati · Updated on 2026-05-04
37
Participants Needed
1
Research Sites
147 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this research study is to determine if lattice radiation therapy (LRT) will provide better treatment for bulky (large) tumors than current standard of care radiotherapy.
CONDITIONS
Official Title
Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Solid tumor malignancy with a clinical indication for radiation
- Patients must have measurable disease
- Target lesion(s) amenable to lattice therapy plan
- Target lesion for radiation must be immobilizable during radiotherapy delivery when applicable
- Age 18 years or older
- ECOG Performance status 2 or better
- Life expectancy greater than 3 months
- Women of child-bearing potential and men must agree to avoid conception by abstinence or birth control prior to and for at least 30 days after lattice therapy
- Ability to understand and willingness to sign informed consent
You will not qualify if you...
- Receiving cytotoxic chemotherapy or radiosensitizing agents within 5 days before or after lattice therapy
- Hematologic malignancies including lymphoma and leukemia
- Primary or metastatic central nervous system malignancies
- History of conditions increasing radiation toxicity
- Known contraindications to radiation therapy
- Uncontrolled intercurrent illness
- Pregnant women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Cincinnati Medical Center
Cincinnati, Ohio, United States, 45219
Actively Recruiting
Research Team
U
UCCC Clinical Trials Office
CONTACT
A
Andrew Frankart, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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