Actively Recruiting

All Genders
NCT06958107

LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients

Led by Wake Forest University Health Sciences · Updated on 2026-01-22

300

Participants Needed

2

Research Sites

227 weeks

Total Duration

On this page

Sponsors

W

Wake Forest University Health Sciences

Lead Sponsor

P

Paula Takacs Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research study is to see how well Low Pass Whole Genome Sequencing (LP-WGS) can detect circulating tumor deoxyribonucleic acid (ctDNA) in the blood of participants who have bone or soft tissue sarcoma (type of cancer).

CONDITIONS

Official Title

LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Written informed consent or assent and HIPAA authorization for release of personal health information
  • All ages allowed
  • Suspected bone or soft tissue tumor concerning for sarcoma pending confirmation
  • Suspected lipomatous mass concerning for ALT or WDLS with planned surgery
  • Confirmed bone or soft tissue sarcoma that is non-metastatic/resectable with planned or current therapy
  • Confirmed metastatic or unresectable sarcoma with planned or current therapy
  • Confirmed non-metastatic sarcoma under surveillance within 1 year of completing therapy
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Levine Cancer Institute

Charlotte, North Carolina, United States, 28204

Actively Recruiting

2

Atrium Health Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, United States, 27103

Actively Recruiting

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Research Team

M

Meg Lattanze

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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LCI-SAR-BSTS-CTDNA-001: Circulating Tumor DNA Liquid Biopsy in Sarcoma Patients | DecenTrialz