Actively Recruiting

Phase 1
Phase 2
Age: 15Years +
FEMALE
NCT06417411

LEARNER- Low dosE AspiRiN prEterm tRial (Angola)

Led by Instituto Nacional de Investigacao em Saude, Angola · Updated on 2024-05-16

450

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

Sponsors

I

Instituto Nacional de Investigacao em Saude, Angola

Lead Sponsor

F

FUNDACIÓN BANCARIA CAIXA D'ESTALVIS I PENSIONS DE BARCELONA

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is being conducted to evaluate the safety and effect of starting daily use of low dose (100 mg) aspirin in pregnant women with sickle cell disease, who are being followed in two county hospitals in Angola, in the first trimester versus the second trimester of the gestational period.

CONDITIONS

Official Title

LEARNER- Low dosE AspiRiN prEterm tRial (Angola)

Who Can Participate

Age: 15Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women with Sickle Cell Disease aged 15 years and older
  • Attending Maternidade Lucrecia Paim, Hospital Materno Infantil Dr. Manuel Pedro Azancot de Menezes, or nearby health facilities
  • Willing to attend regular consultations and consent to participate in the study
Not Eligible

You will not qualify if you...

  • Pregnant women with Sickle Cell Disease in the third trimester (after week 27)
  • HIV infection
  • Diabetes mellitus
  • Chronic hypertension
  • Liver disease with lab values 3 times above normal
  • Sickle nephropathy
  • Multiple pregnancies
  • Hypersensitivity to aspirin
  • History of blood transfusion in the last 3 months
  • Did not consent to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Instituto Nacional de Investigação Em Saúde

Luanda, Angola, 00000

Actively Recruiting

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Research Team

T

TATIANA GOMES, BA/BS/Pre-MD

CONTACT

H

HELENA TEIXEIRA, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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