Actively Recruiting

Phase Not Applicable
Age: 4Years - 7Years
All Genders
NCT06267430

Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD

Led by Erasmus Medical Center · Updated on 2024-11-29

141

Participants Needed

3

Research Sites

191 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Advances in prenatal and neonatal care have improved outcomes in children with severe congenital heart disease (CHD). With the increase in survival, neurocognitive problems such as executive functioning (EF) impairments have become more apparent in these children. EF problems have cascading negative effects on a child's development. New insights in EF development suggest that in otherwise physically healthy young children, EF can be improved by training. In a pilot study funded by Stichting Hartekind, the investigators studied the feasibility of a personalized EF training program called 'Kleuter Extra' and the results were promising. Therefore, the current study will investigate the effectiveness of this program in 4-6-year-old children with severe CHD. The researchers will also explore interactions between the parent-child relationship and EF development of the child as psychosocial difficulties in these children and their parent(s) and/or caretaker(s) may impact EF-development. If found effective, EF training for children with severe CHD will improve their developmental outcome.

CONDITIONS

Official Title

Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD

Who Can Participate

Age: 4Years - 7Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Child aged 4.0 to 6.0 years, or aged 6.0 to 7.0 years and still in kindergarten
  • Child had congenital heart disease surgery within the first six months of life or cyanotic CHD surgery within the first 12 months
  • Child has an estimated IQ greater than 55 (no moderate to severe intellectual disability)
  • Child shows diminished executive functioning (score at or below 25th percentile on KleuterExtra test battery)
  • Child understands Dutch well enough to participate in tests and training
  • Parent(s) understand Dutch well enough to understand study information and complete questionnaires
Not Eligible

You will not qualify if you...

  • Child is currently receiving targeted executive functioning support at school
  • Child has severe brain damage with estimated IQ below 55
  • Child has genetic syndromes that affect cognitive performance, such as Down syndrome
  • Child has severe psychiatric disorders needing treatment first, including posttraumatic stress disorder, separation anxiety disorder, or reactive attachment disorder

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

University Medical Center - Beatrix children's hospital Groningen

Groningen, Netherlands, 9713GZ

Actively Recruiting

2

Erasmus Medical Center Sophia Children's Hospital

Rotterdam, Netherlands, 3015CN

Actively Recruiting

3

University Medical Center - Wilhelmina children's hospital Utrecht

Utrecht, Netherlands, 3584EA

Not Yet Recruiting

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Research Team

E

Eveline Oppelaar

CONTACT

A

André Rietman

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

2

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Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD | DecenTrialz