Actively Recruiting
Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate
Led by University Hospital Bispebjerg and Frederiksberg · Updated on 2026-01-15
1000
Participants Needed
1
Research Sites
595 weeks
Total Duration
On this page
Sponsors
U
University Hospital Bispebjerg and Frederiksberg
Lead Sponsor
R
Rigshospitalet, Denmark
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram. In connection with the operation, the small pouch known as the auricle of the heart is closed, which can be completely removed after closing. This procedure is common in patients with atrial fibrillation to protect the brain from stroke. In the project, all patients will have this auricle closed if they agree to participate in the project. After closure, the auricle is usually discarded. We will analyze the blood and the auricle tissue taken (if available) in connection with the operation itself, together with the analysis of the electrocardiogram recorded before the planned heart operation.
CONDITIONS
Official Title
Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent
- Planned open-heart surgery such as coronary artery bypass grafting (CABG), valve repair or replacement, aorta surgery, or any combination of these procedures
You will not qualify if you...
- Current endocarditis
- Unable to participate in follow-up after surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rigshospitalet
Copenhagen, Denmark
Actively Recruiting
Research Team
H
Helena DOMINGUEZ, MD, PhD
CONTACT
I
Ida Gustafsson, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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