Actively Recruiting
Left Bundle Branch Area Pacing in Heart Failure Patients With Ejection Fraction Below Normal
Led by Seoul National University Hospital · Updated on 2025-05-18
200
Participants Needed
1
Research Sites
168 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
While cardiac resynchronization therapy remains the mainstay for advanced HF, it is not always feasible due to unfavorable anatomy of coronary sinus or pacing characteristics. In such cases, left bundle branch area pacing itself or left bundle optimized cardiac resynchronization therapy could be a rescue therapy for failed or unsuccessful biventricular cardiac resynchronization therapy. However, the efficacy and safety of left bundle branch area pacing (or left bundle optimized cardiac resynchronization therapy) as rescue therapy for biventricular cardiac resynchronization therapy is largely hypothetic and lack concrete evidence still. Therefore, there is an unmet need for the registry purposed for left bundle branch area pacing among heart failure with mid-range (or mildly reduced) ejection fraction and heart failure with reduced ejection fraction patients to investigate its efficacy and safety. This study aims to investigate the efficacy and safety of left bundle branch area pacing in heart failure patients with ejection fraction below normal using Selectra catheters.
CONDITIONS
Official Title
Left Bundle Branch Area Pacing in Heart Failure Patients With Ejection Fraction Below Normal
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients previously diagnosed with heart failure with mid-range (or mildly reduced) ejection fraction and heart failure with reduced ejection fraction, documented by echocardiographic study showing left ventricular ejection fraction below 50%
- Patients with indications for cardiac pacing or cardiac resynchronization therapy
You will not qualify if you...
- Patients younger than 19 years old
- Pregnant patients
- Patients with an expected life expectancy of less than 1 year
- Patients with a mechanical valve in the tricuspid valve
- Patients who require atrial pacing only
- Patients unable to receive a transvenous pacemaker for any reason
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Seoul National University Hospital
Seoul, Jongno-gu, South Korea, 03080
Actively Recruiting
Research Team
E
Eue-Keun Choi, M.D. Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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