Actively Recruiting
Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock
Led by University of Minnesota · Updated on 2025-08-03
200
Participants Needed
1
Research Sites
230 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A Clinical Events Committee (CEC) will include Cardiac Surgery Professor and chief of cardiac surgery Rose Kelly MD, Professor of Medicine Ganesh Raveendran MD at the University of Minnesota who is the direction of Interventional Cardiology and Professor of Medicine at the University of Minnesota David Benditt. They will review and adjudicate serious and unexpected adverse events independently from the PI and co investigators.
CONDITIONS
Official Title
Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 75 years
- SCAI D/E cardiogenic shock requiring VA-ECMO support as determined by the treating team
- Mean arterial pressure (MAP) greater than 65 mmHg while on fewer than 3 vasopressors or inotropes at consent
- Cardiogenic shock due to acute coronary syndrome confirmed by coronary angiography during the current hospital stay
You will not qualify if you...
- Use of VA-ECMO for sepsis, pulmonary embolism, COVID-19 related cardiorespiratory failure, or severe right ventricular failure due to severe idiopathic pulmonary hypertension
- Cardiogenic shock from causes other than acute coronary syndrome
- Severe left ventricular dysfunction with stage IV NYHA heart failure, history of LVAD, or heart transplantation before starting VA-ECMO
- Profound vasoplegia with MAP less than 65 mmHg while on 3 vasopressors or inotropes
- Moderate to severe aortic regurgitation or aortic stenosis contraindicating VA-ECMO or left ventricular catheterization
- Bleeding complications needing ongoing blood transfusions
- Ischemic lower extremities
- Evidence of circuit thrombosis or fibrin buildup
- Evidence of sepsis or septic shock
- Presence of left ventricular thrombus on echocardiography
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Actively Recruiting
Research Team
J
Julie Longman
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here