Actively Recruiting
Lesion Formation With Pulsed Field Versus Cryobaloon Ablation as Assessed by Cardiac Magnetic Resoncance
Led by Hospital Clinic of Barcelona · Updated on 2026-04-07
104
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomised study will compare pulsed field ablation and cryoballoon ablation with respect to ablation lesion quality as assessed by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) at 3 months post-ablation. Patients scheduled for first-time AF ablation will be randomised in a 2:1 fashion to receive PVI-only, either by pulsed field ablation (Farapulse Pulsed Field Ablation System, Boston Scientific) or cryoballoon ablation (Medtronic Cryoballoon Ablation System).
CONDITIONS
Official Title
Lesion Formation With Pulsed Field Versus Cryobaloon Ablation as Assessed by Cardiac Magnetic Resoncance
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled for first-time atrial fibrillation catheter ablation
You will not qualify if you...
- Age under 18 years
- Long-standing persistent atrial fibrillation
- Prior left atrial ablation
- Pregnancy or lactation
- Reduced left ventricular ejection fraction
- Glomerular filtration rate (GFR) under 30%
- Body mass index (BMI) over 35%
- Left atrial diameter over 55 mm
- Presence of cardiac implantable electronic device
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital Clinic, University of Barcelona
Barcelona, Catalonia, Spain, 08036
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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