Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
All Genders
Healthy Volunteers
NCT07344298

Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function

Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2026-03-27

72

Participants Needed

1

Research Sites

95 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire de Saint Etienne

Lead Sponsor

L

Laboratoire Interuniversitaire de Biologie de la Motricité

Collaborating Sponsor

AI-Summary

What this Trial Is About

Local vibration is a non-invasive neuromuscular stimulation modality used in training and rehabilitation for its effects on neuromuscular function, particularly its ability to induce nervous adaptations. Its passive application is particularly useful in cases of motor deficit or immobilization. Several studies, including our own, have shown that vibration protocols over several weeks can induce significant gains in muscle strength, particularly in the knee extensors. However, the parameters of application remain heterogeneous, particularly with regard to the duration of the interventions. With this in mind, a prospective controlled study is being conducted in healthy subjects, comparing four modalities of local vibration intervention targeting the knee extensors: an intensive vibration protocol over 5 consecutive days (1 session of 30 or 60 minutes per day) and a protocol spread over 4 weeks at a rate of 3 weekly sessions of 30 or 60 minutes). The objective is to evaluate and compare their immediate and delayed effects on force production and corticospinal properties. The results of this study will thus help optimize recommendations regarding the use of local vibration in muscle strengthening and neuromuscular reconditioning strategies.

CONDITIONS

Official Title

Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function

Who Can Participate

Age: 18Years - 45Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women
  • Aged between 18 and 45
  • Body mass index between 18 and 30 kg/m²
  • Given detailed information and signed consent form with investigator
  • Affiliated with or entitled to social security coverage
Not Eligible

You will not qualify if you...

  • Chronic cardiovascular, neuromuscular, bone, metabolic, or inflammatory conditions
  • Personal history or risk factors for thrombosis
  • Undergoing antidepressant treatment
  • Taken corticosteroids in the last 3 months
  • Use of neuroactive substances affecting corticospinal excitability during study
  • Bone or ligament trauma to lower limbs within last 12 months
  • Unable to perform required physical efforts
  • Engaged in intense or unusual physical activity including competitive sports in month before and during protocol
  • Skin lesion at vibration site
  • Participating in another interventional medical trial
  • Pregnant or breastfeeding women
  • Unable to understand study purpose or give consent
  • Deprived of liberty or under legal protection such as guardianship

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

CHU de Saint-Etienne

Saint-Etienne, France, 42055

Actively Recruiting

Loading map...

Research Team

L

Léonard FEASSON, MD, PhD

CONTACT

T

Thomas LAPOLE, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

4

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here