Actively Recruiting
Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function
Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2026-03-27
72
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
Sponsors
C
Centre Hospitalier Universitaire de Saint Etienne
Lead Sponsor
L
Laboratoire Interuniversitaire de Biologie de la Motricité
Collaborating Sponsor
AI-Summary
What this Trial Is About
Local vibration is a non-invasive neuromuscular stimulation modality used in training and rehabilitation for its effects on neuromuscular function, particularly its ability to induce nervous adaptations. Its passive application is particularly useful in cases of motor deficit or immobilization. Several studies, including our own, have shown that vibration protocols over several weeks can induce significant gains in muscle strength, particularly in the knee extensors. However, the parameters of application remain heterogeneous, particularly with regard to the duration of the interventions. With this in mind, a prospective controlled study is being conducted in healthy subjects, comparing four modalities of local vibration intervention targeting the knee extensors: an intensive vibration protocol over 5 consecutive days (1 session of 30 or 60 minutes per day) and a protocol spread over 4 weeks at a rate of 3 weekly sessions of 30 or 60 minutes). The objective is to evaluate and compare their immediate and delayed effects on force production and corticospinal properties. The results of this study will thus help optimize recommendations regarding the use of local vibration in muscle strengthening and neuromuscular reconditioning strategies.
CONDITIONS
Official Title
Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women
- Aged between 18 and 45
- Body mass index between 18 and 30 kg/m²
- Given detailed information and signed consent form with investigator
- Affiliated with or entitled to social security coverage
You will not qualify if you...
- Chronic cardiovascular, neuromuscular, bone, metabolic, or inflammatory conditions
- Personal history or risk factors for thrombosis
- Undergoing antidepressant treatment
- Taken corticosteroids in the last 3 months
- Use of neuroactive substances affecting corticospinal excitability during study
- Bone or ligament trauma to lower limbs within last 12 months
- Unable to perform required physical efforts
- Engaged in intense or unusual physical activity including competitive sports in month before and during protocol
- Skin lesion at vibration site
- Participating in another interventional medical trial
- Pregnant or breastfeeding women
- Unable to understand study purpose or give consent
- Deprived of liberty or under legal protection such as guardianship
AI-Screening
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Trial Site Locations
Total: 1 location
1
CHU de Saint-Etienne
Saint-Etienne, France, 42055
Actively Recruiting
Research Team
L
Léonard FEASSON, MD, PhD
CONTACT
T
Thomas LAPOLE, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
4
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