Actively Recruiting

Age: 18Years +
All Genders
NCT06317831

LetS Get fUnctional! FuNctional Status in pEople With intersTitial Lung Disease

Led by Aveiro University · Updated on 2024-04-30

150

Participants Needed

1

Research Sites

225 weeks

Total Duration

On this page

Sponsors

A

Aveiro University

Lead Sponsor

F

Fundação para a Ciência e a Tecnologia

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to i) To characterize the functional status and explore the determinants of functional status decline of people with IlD ii)To determine the measurement properties of functional status instruments in people with Interstitial lung diseases (ILD) iii) To identify the impact of ILD and the participants' perspectives on functional status through interviews iv) Explore the progression of functional status progression in people with ILD and v) Develop a multidimensional index, incorporating functional status parameters, to predict mortality in people with ILD. Patients with ILD will be recruited via the pulmonology services at hospitals, namely from Centro Hospitalar de Vila Nova de Gaia/Espinho (CHVNG/E), Centro Hospitalar do Baixo Vouga (CHBV) and Centro Hospitalar de Entre o Douro e Vouga (CHEDV). Sociodemographic, clinical characteristics (i.e., smoking habits, vital signs and symptoms), anthropometric (i.e., height and weight to compute body mass index) and general clinical data (i.e., medication, oxygen therapy, non-invasive ventilation, acute exacerbations, hospitalizations and number of hospital admissions in the last month and year, length of stay), as well as prior and follow-up spirometric measurements and arterial blood gas will be collected from clinical records for patients' characterization. Mortality and rehospitalizations will be explored during the study period. Peripheral muscle strength, functional status, daily physical activity, self-reported symptoms, functional status, impact of the disease and health-related quality of life. Qualitative data from interviews. The assessments will be conducted at 6 time points: baseline and 1 week after for instrument validation, followed by assessments every 6 months for 2 years. It is expected that: i) Functional status limitations can be comprehensively identified and measured in individuals with ILD. ii) Some measures are valid and reliable indicators of functional status in individuals with ILD. iii) Different profiles of functional status progression will be identified in individuals with ILD, including stable, slow, and fast decline. iv) A multidimensional index incorporating functional status will improve the accuracy of predicting mortality and outperform the predictive ability of the current GAP Index.

CONDITIONS

Official Title

LetS Get fUnctional! FuNctional Status in pEople With intersTitial Lung Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Diagnosed with any type of interstitial lung disease (ILD)
  • Fluent in Portuguese
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Other respiratory diseases
  • History of acute cardiac or respiratory condition in the previous month
  • Signs of cognitive impairment
  • Significant cardiovascular, neurological, or musculoskeletal disease limiting participation
  • Current cancer (neoplasia)
  • Other autoimmune diseases besides ILD

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Aveiro

Aveiro, Portugal, 3810-193

Actively Recruiting

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Research Team

A

Alda S. Marques, PhD

CONTACT

O

Odete M. Alves, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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