Actively Recruiting
LetS Get fUnctional! FuNctional Status in pEople With intersTitial Lung Disease
Led by Aveiro University · Updated on 2024-04-30
150
Participants Needed
1
Research Sites
225 weeks
Total Duration
On this page
Sponsors
A
Aveiro University
Lead Sponsor
F
Fundação para a Ciência e a Tecnologia
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to i) To characterize the functional status and explore the determinants of functional status decline of people with IlD ii)To determine the measurement properties of functional status instruments in people with Interstitial lung diseases (ILD) iii) To identify the impact of ILD and the participants' perspectives on functional status through interviews iv) Explore the progression of functional status progression in people with ILD and v) Develop a multidimensional index, incorporating functional status parameters, to predict mortality in people with ILD. Patients with ILD will be recruited via the pulmonology services at hospitals, namely from Centro Hospitalar de Vila Nova de Gaia/Espinho (CHVNG/E), Centro Hospitalar do Baixo Vouga (CHBV) and Centro Hospitalar de Entre o Douro e Vouga (CHEDV). Sociodemographic, clinical characteristics (i.e., smoking habits, vital signs and symptoms), anthropometric (i.e., height and weight to compute body mass index) and general clinical data (i.e., medication, oxygen therapy, non-invasive ventilation, acute exacerbations, hospitalizations and number of hospital admissions in the last month and year, length of stay), as well as prior and follow-up spirometric measurements and arterial blood gas will be collected from clinical records for patients' characterization. Mortality and rehospitalizations will be explored during the study period. Peripheral muscle strength, functional status, daily physical activity, self-reported symptoms, functional status, impact of the disease and health-related quality of life. Qualitative data from interviews. The assessments will be conducted at 6 time points: baseline and 1 week after for instrument validation, followed by assessments every 6 months for 2 years. It is expected that: i) Functional status limitations can be comprehensively identified and measured in individuals with ILD. ii) Some measures are valid and reliable indicators of functional status in individuals with ILD. iii) Different profiles of functional status progression will be identified in individuals with ILD, including stable, slow, and fast decline. iv) A multidimensional index incorporating functional status will improve the accuracy of predicting mortality and outperform the predictive ability of the current GAP Index.
CONDITIONS
Official Title
LetS Get fUnctional! FuNctional Status in pEople With intersTitial Lung Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Diagnosed with any type of interstitial lung disease (ILD)
- Fluent in Portuguese
- Able to provide informed consent
You will not qualify if you...
- Other respiratory diseases
- History of acute cardiac or respiratory condition in the previous month
- Signs of cognitive impairment
- Significant cardiovascular, neurological, or musculoskeletal disease limiting participation
- Current cancer (neoplasia)
- Other autoimmune diseases besides ILD
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Aveiro
Aveiro, Portugal, 3810-193
Actively Recruiting
Research Team
A
Alda S. Marques, PhD
CONTACT
O
Odete M. Alves, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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