Actively Recruiting
Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry
Led by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University · Updated on 2026-03-03
420
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
S
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Lead Sponsor
A
AstraZeneca
Collaborating Sponsor
AI-Summary
What this Trial Is About
The COPD in LCS Registry will identify and characterize individuals who have functional or radiographic evidence of COPD and are receiving lung cancer screening. Clinical information will be obtained from study participants including symptom burden, lung cancer risk, spirometry, imaging characteristics, and peripheral blood eosinophils.
CONDITIONS
Official Title
Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Eligible for lung cancer screening by USPSTF 2021 criteria including age 50-80 years and current or former smoker with at least 20 pack-years
- Willing to participate in an observational clinical trial and be contacted about future studies
- Able to tolerate study procedures
- Able to provide informed consent
- Lung cancer screening CT performed at the University of Michigan within the last year
- Meets one of the following: prior COPD diagnosis, lung function test showing COPD, or lung scan showing emphysema over 1%
You will not qualify if you...
- Have a lung condition other than COPD or asthma or another condition causing breathing symptoms
- Severe asthma defined by high-dose inhaled steroids or frequent asthma healthcare visits or hospitalizations
- Currently participating in a blinded therapeutic trial
- Currently pregnant; birth control documentation required for pre-menopausal women
- Cognitive problems preventing study participation
- Body mass index over 35 kg/m2
- Current illicit drug use including cannabis smoking
- Illness expected to cause death within 3 years
- Implanted metal devices or prosthesis above the waist affecting CT scan quality
- History of chest radiation or lung surgery that removed lung tissue
- Acute COPD flare-up or recent antibiotic or steroid use for infection unless stable for 30 days
- Use of chronic prednisone under certain low doses or chronic antibiotic therapy allowed
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Thomas Jefferson University
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
Research Team
J
Julie Barta, MD, ATSF
CONTACT
Y
Yolanda Kry, BS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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