Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05675735

Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder

Led by NYU Langone Health · Updated on 2026-01-28

318

Participants Needed

4

Research Sites

239 weeks

Total Duration

On this page

Sponsors

N

NYU Langone Health

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Using a stepped-wedge randomized controlled trial, the study will test whether a clinic-level multidimensional intervention conducted in 36 opioid treatment programs (OTPs) will improve clinical decision making, regulatory confusion, legal liability concerns, capacity for clinical practice change, and financial barriers to take- home dosing (THD) for methadone as compared to treatment as usual.

CONDITIONS

Official Title

Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinic staff working at selected opioid treatment programs chosen by the OASAS client data system
  • Patients aged 18 or older
  • Patients receiving take-home methadone treatment for at least 30 days
Not Eligible

You will not qualify if you...

  • Children and adolescents are excluded from this study
  • No exclusion based on sex or gender to increase generalizability

AI-Screening

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Trial Site Locations

Total: 4 locations

1

University of Connecticut

Storrs, Connecticut, United States, 06268

Actively Recruiting

2

University at Buffalo

Buffalo, New York, United States, 14260

Actively Recruiting

3

NYU Langone Health

New York, New York, United States, 10016

Actively Recruiting

4

Weill Cornell Medical College

New York, New York, United States, 10065

Actively Recruiting

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Research Team

C

Charles Neighbors, PhD

CONTACT

B

Beth Knopf, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

6

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