Actively Recruiting
Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant
Led by Johns Hopkins University · Updated on 2026-04-13
65
Participants Needed
1
Research Sites
140 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Can the investigators create an effective way to improve adherence to immunosuppressant medication and reduce rejection, graft loss, and death in adolescents and young adults who have undergone kidney or liver transplantation? The investigators' mobile technology intervention uses real-time electronic pillbox-assessed dose timing and text message prompts to address antirejection medication nonadherence when nonadherence is detected.
CONDITIONS
Official Title
Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adolescents and young adults aged 13 to 25 years
- Underwent kidney or liver transplantation at least 6 months before enrollment
- Currently prescribed tacrolimus or sirolimus medication
You will not qualify if you...
- Currently receiving dialysis
- Hospitalized for the duration of the study
- Significant developmental or cognitive delay
- No access to a mobile device that supports text messaging
- Decline to use the electronic pillbox to monitor daily medication adherence
- Non-English speaking
- If graft failure occurs potentially leading to dialysis, continuation in the study is optional if remaining on tacrolimus or sirolimus
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Johns Hopkins
Baltimore, Maryland, United States, 21287
Actively Recruiting
Research Team
C
Cyd Eaton, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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