Actively Recruiting
Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea
Led by The First Affiliated Hospital of Soochow University · Updated on 2025-11-21
42
Participants Needed
1
Research Sites
77 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Objectives: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers analgesic effects. Methods: A total of 42 IBS-D patients were recruited and randomly assigned (1:1) to the sham rTMS or the rTMS group. A nested cohort of 21 IBS-D participants who completed baseline fMRI assessments prior to randomization was included. Consistent with the randomization procedure，these individuals were evenly distributed between the two groups. Both participants and outcome assessors remained blinded to treatment allocation throughout the study. All patients completed the two-week intervention and were included in the final analysis.
CONDITIONS
Official Title
Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- Diagnosis of IBS-D according to Rome IV criteria
You will not qualify if you...
- Presence of inflammatory or other organic gastrointestinal diseases
- Diagnosed psychiatric disorders
- History of anorectal, intestinal, or abdominal surgery
- Pregnancy or lactation
- Presence of metallic implants or cardiac pacemakers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China, 215006
Actively Recruiting
Research Team
R
Ruixia Weng, Dr.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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