Actively Recruiting
Lidocaine Infusion in Pancreatic Cancer
Led by University of Illinois at Chicago · Updated on 2025-03-03
46
Participants Needed
1
Research Sites
373 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study elucidates the effects of the intravenous (IV) lidocaine infusion on the biology of pancreatic circulating tumor cells (CTCs) isolated from patients undergoing robotic pancreatectomy for all types of pancreatic cancer. A prospective randomized controlled double blinded trial design will be used for the proposed study.
CONDITIONS
Official Title
Lidocaine Infusion in Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically or cytologically confirmed resectable adenocarcinoma or other pancreatic cancers
- Has at least one measurable tumor
- Patients found to have metastatic disease during initial surgical exploration
- Has read, understood, and signed informed consent approved by IRB/IEC
- Prior systemic treatments for metastatic disease allowed, including targeted therapies and chemotherapy
You will not qualify if you...
- American Society of Anesthesiologists (ASA) physical status greater than 3
- Allergy or hypersensitivity to amide-linked local anesthetics
- Second or third degree heart block
- Severe sinoatrial block
- Current treatment with class I antiarrhythmic drugs: quinidine, flecainide, disopyramide, or procainamide
- Previous treatment with amiodarone
- Adams-Stoke syndrome
- Wolff-Parkinson-White syndrome
- History of blood clots, pulmonary embolism, or deep vein thrombosis unless controlled with anticoagulants
- Known HIV positivity or untreated/uncontrolled hepatitis B or C
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Illnois at Chicago
Chicago, Illinois, United States, 60612
Actively Recruiting
Research Team
A
Alexandra Barabanova, MS
CONTACT
G
Gina E. Votta-Velis, MD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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