Study Comparing Lidocaine Alone Versus Lidocaine with Dexmedetomidine for Intravenous Regional Anesthesia in Upper Limb Surgery

What this Trial Is About

Researchers are evaluating the use of lidocaine alone versus lidocaine combined with dexmedetomidine for intravenous regional anesthesia IVRA in upper limb surgery. The study aims to compare these treatments in terms of pain levels and the duration of pain relief after surgery. IVRA involves using a pneumatic tourniquet and injecting a local anesthetic to numb the limb during surgeries lasting less than one hour. This technique has some limitations such as tourniquet pain and limited postoperative pain control, so this research explores whether adding dexmedetomidine can improve outcomes. The study compares two groups one receiving 40 ml of 0.5% lidocaine alone, and the other receiving the same lidocaine dose combined with dexmedetomidine at 0.5 micrograms per kilogram. Dexmedetomidine is an alpha-2 adrenergic receptor agonist known for its sedative and pain-relieving effects. Participants will undergo intravenous regional anesthesia with these medications administered below the tourniquet, which isolates the limb for surgery. Participants will be monitored for pain relief duration up to 24 hours after surgery and pain scores measured by a visual analogue scale two hours post-operation. The study is randomized without blinding. Researchers will assess how long postoperative pain relief lasts and how intense the pain is during recovery. The trial involves elective surgeries lasting under 45 minutes and tracks outcomes to better understand how these medications work in this setting.

Lidocaine vs. Lidocaine With Dexmedetomidine for Intravenous Regional Anesthesia (IVRA) in Upper Limb Surgery