Actively Recruiting
Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
Led by St. Anne's University Hospital Brno, Czech Republic · Updated on 2025-06-27
48
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
Sponsors
S
St. Anne's University Hospital Brno, Czech Republic
Lead Sponsor
S
Slovak Academy of Sciences
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau protein), physical fitness, and metabolism in older adults at increased risk of developing Alzheimer's disease.
CONDITIONS
Official Title
Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 60 to 80 years
- Diagnosis of Subjective Cognitive Impairment (SCI) or Mild Cognitive Impairment (MCI)
- Mini-mental-scale (MMSE) score between 24 and 30
- Positive plasma pTau217 biomarker
- Stable dose of iAChE therapy if applicable
- Ability to participate in a 9-month intervention
You will not qualify if you...
- Stroke or heart attack within the past year
- Severe internal medical conditions such as heart failure, kidney failure, unstable diabetes, or use of GLP1 agonist therapy
- Long-term psychiatric treatment except well-managed depression
- Neurological diseases affecting movement or thinking, like Parkinson's disease, severe tremor, or epilepsy
- Severe sensory or motor problems preventing participation
- Active cancer treated in the last 5 years
- Expected poor compliance due to transport, time, or cooperation issues
- Participation in another clinical study
- Unstable iAChE medication regimen
- Dependence on substances or alcohol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fnusa/ Icrc
Brno, Czechia, 64400
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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