Actively Recruiting

Phase Not Applicable
Age: 10Years - 14Years
All Genders
NCT07466069

Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents

Led by University of Sao Paulo · Updated on 2026-03-12

24

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Transgender and gender-diverse adolescents are at increased risk for obesity, disordered eating behaviors, body dissatisfaction, and reduced quality of life due to minority stress and structural inequities. However, no structured lifestyle interventions specifically tailored to this population have been developed. This randomized controlled trial aims to evaluate the effectiveness of a 6-month interdisciplinary lifestyle intervention designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents aged 10-14 years. Participants will be randomized (1:1) to either an intervention group receiving monthly group sessions (for adolescents and caregivers separately) and weekly supportive messages, or a control group receiving standard outpatient care and general health recommendations. The primary outcome is quality of life measured by the WHOQOL-BREF. Secondary outcomes include eating disorder symptoms, body image, diet quality, physical activity levels, sedentary behavior, body composition, and anthropometric measures.

CONDITIONS

Official Title

Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents

Who Can Participate

Age: 10Years - 14Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 10 to 14 years
  • Self-identified as transgender or gender-diverse
Not Eligible

You will not qualify if you...

  • Current diagnosis of eating disorder requiring specialized treatment
  • Severe psychiatric instability
  • Cognitive impairment limiting participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

São Paulo, São Paulo, Brazil, 05403010

Actively Recruiting

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Research Team

B

Bruno Gualano, PhD

CONTACT

B

Bruna Caruso Mazzolani, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents | DecenTrialz