Actively Recruiting
Lifestyle Intervention in Patients With Metastatic Prostate Cancer
Led by Oncology Institute of Southern Switzerland · Updated on 2025-11-18
30
Participants Needed
1
Research Sites
161 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The proposed pilot study aims at determining the feasibility of a lifestyle intervention including adherence to a personalised dietary regimen combined with regular physical activity in patients newly diagnosed with prostate cancer under androgen deprivation therapy.
CONDITIONS
Official Title
Lifestyle Intervention in Patients With Metastatic Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Written informed consent according to ICH/GCP regulations before registration
- Age 18 years or older
- Histology of adenocarcinoma of the prostate
- Patients receiving androgen deprivation therapy alone or combined with novel hormonal agents (abiraterone, enzalutamide, apalutamide, or darolutamide)
- Rising PSA with two consecutively rising levels more than 25% above nadir at least three weeks apart
- PSA doubling time greater than 8 weeks
- Ongoing systemic treatment continuation feasible as deemed by treating physician
You will not qualify if you...
- Ongoing treatment with docetaxel, cabazitaxel, radionuclides, or investigational treatments
- Evidence of clinical progression or progression on imaging
- Bone metastases that exclude safety of physical exercise
- Prior severe osteoporosis or bone diseases with fracture history
- Clinically significant cardiovascular disease such as recent myocardial infarction, uncontrolled angina, severe heart failure, significant arrhythmias, or uncontrolled hypertension
- Clinically significant chronic obstructive pulmonary disease
- Any other disease or condition interfering with study participation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Oncology Institute of Southern Switzerland (IOSI)
Bellinzona, Switzerland, 6500
Actively Recruiting
Research Team
U
Ursula Vogl, MD
CONTACT
L
Luigi Tortola, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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