Actively Recruiting
Lifestyle Patterns and Glycemic Control
Led by Columbia University · Updated on 2026-01-28
34
Participants Needed
1
Research Sites
236 weeks
Total Duration
On this page
Sponsors
C
Columbia University
Lead Sponsor
D
Department of Health and Human Services
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of the proposed study is to evaluate the feasibility and initial efficacy of stabilizing lifestyle behaviors to improve glucose control and body composition in patients with pre-diabetes. The investigator proposes that following stable lifestyle behaviors will improve patients' glucose control, body composition, and liver fat. The results from this study has the potential to impact clinical practice and patient care.
CONDITIONS
Official Title
Lifestyle Patterns and Glycemic Control
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with pre-diabetes (hemoglobin A1c 5.7-6.9%)
- 25 years or older
- Body mass index (BMI) between 25 and 39.9 kg/m2
- Sleep at least 6 hours per night, measured over 14 nights with wrist actigraphy
- Variable bedtime with a standard deviation of 45 minutes or more
You will not qualify if you...
- Chronic kidney disease with glomerular filtration rate (GFR) less than 60
- Uncontrolled high blood pressure (160/100 mmHg or higher)
- Obstructive sleep apnea
- Psychiatric or neurological disorders
- Existing cardiovascular disease
- Dyslipidemia with triglycerides 200 mg/dL or higher
- Use of medications affecting insulin sensitivity, glucose levels, or body weight
- Working non-day or rotating shifts
- Recent travel across time zones
- Active or recent (within 3 months) participation in a weight loss program
- Current or past alcohol or drug abuse
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Columbia University Irving Medical Center
New York, New York, United States, 10032
Actively Recruiting
Research Team
M
Marie-Pierre St-Onge
CONTACT
L
Lena Navarro
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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