Actively Recruiting

Age: 45Years - 70Years
MALE
Healthy Volunteers
NCT03711539

Lifetime Endurance Exercise to Prevent Coronary Artery Disease

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-03

1800

Participants Needed

3

Research Sites

362 weeks

Total Duration

On this page

Sponsors

U

Universitaire Ziekenhuizen KU Leuven

Lead Sponsor

U

University Hospital, Antwerp

Collaborating Sponsor

AI-Summary

What this Trial Is About

The primary objective of the Master@Heart Trial is to investigate whether lifelong endurance exercise reduces the incidence of non-calcified plaques (both mixed and soft plaques) as compared to late-onset endurance exercise and a non-athletic lifestyle.

CONDITIONS

Official Title

Lifetime Endurance Exercise to Prevent Coronary Artery Disease

Who Can Participate

Age: 45Years - 70Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male participants aged 45 to 70 years
  • Lifelong endurance athletes who started endurance sports before age 30 and compete at regional, national, or international levels
  • Lifelong athletes involved in triathlon, cycling, distance running (1500 meters and longer), or rowing
  • Lifelong athletes training more than 10 hours weekly for cyclists and triathletes, or more than 6 hours weekly for runners and rowers
  • Late-onset endurance athletes who started endurance sports after age 30 at least 6 months ago and compete at regional, national, or international levels
  • Late-onset athletes involved in triathlon, cycling, distance running (1500 meters and longer), or rowing
  • Late-onset athletes training more than 10 hours weekly for cyclists and triathletes, or more than 6 hours weekly for runners and rowers
  • Healthy non-athletes with less than 3 hours per week of regular sports practice
  • Non-athletes allowed to participate in low dynamic sports (e.g., billiards, darts, bowling) more than 3 hours per week
  • Non-athletes recruited from outpatient clinics for work-related medical check-ups, university alumni, or multisports organizations
Not Eligible

You will not qualify if you...

  • History of smoking more than 5 pack years
  • History of diabetes
  • Prior diagnosis of any cardiopulmonary disorder
  • Current medical treatment for arterial hypertension or hypercholesterolemia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

University Hospital, Antwerpen

Edegem, Belgium, 2650

Actively Recruiting

2

Jessa Hospital

Hasselt, Belgium, 3500

Actively Recruiting

3

UZLeuven

Leuven, Belgium, 3000

Actively Recruiting

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Research Team

G

Guido Claessen, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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