Actively Recruiting
LIFUS For Neurological Disorders
Led by University Health Network, Toronto · Updated on 2026-02-18
50
Participants Needed
1
Research Sites
786 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Low intensity focused ultrasound (LIFUS) has the potential to be used as a means of non-invasive neuro-modulation. To this day, the use of LIFUS is under investigation. Studies in healthy subjects have shown that application of LIFUS to the motor region of the brain can mildly decrease neuron excitability in healthy controls. The purpose of the present study is to evaluate the effects of LIFUS on brain tissue excitability in patients with movement disorders in order to elucidate the therapeutic potential of LIFUS.
CONDITIONS
Official Title
LIFUS For Neurological Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 85 years of age
- Diagnosed with neurological disorders such as epilepsy, brain tumor, movement disorders, or psychiatric disorders such as substance abuse disorder
- Undergoing medical or surgical treatment, including deep brain stimulation, for neurological disorders
You will not qualify if you...
- History of stroke
- Comorbid dementia
- Scored below 22 on the Montreal Cognitive Assessment (MoCA)
- Implanted cardiac pacemaker or implantable cardioverter-defibrillator (ICD)
- Presence of metal implants contraindicated for TMS or MRI
- Pregnancy
- Major depression or psychiatric disorder affecting understanding or willingness to follow study procedures
- Taking psychotropic medications or recreational substances that could affect safety
- Major systemic illness or infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Toronto Western Hospital, 399 Bathurst St
Toronto, Ontario, Canada, M5T 2S8
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here