Light Stimulation to Improve Vision in Adults Aged 18 to 60 With Multiple Sclerosis After Recent Optic Neuritis

What this Trial Is About

Researchers are evaluating a light stimulation treatment to improve visual function in people with multiple sclerosis who have recently experienced optic neuritis. This randomized controlled study aims to understand how intense visual stimulation might help regenerate the visual system. The study compares the effects of light stimulation with a control group receiving sham treatment to observe natural recovery progress. Participants in the treatment group will watch a flickering video on a mobile phone twice daily for 80 seconds each session, over 12 days. The control group will view a white screen for the same duration and frequency. This standardized light exposure is designed to stimulate the visual pathway and promote recovery after optic neuritis. Throughout the study, participants will undergo tests of visual sensitivity, including high and low contrast measures, and visual evoked potentials. Imaging tests like optical coherence tomography and angiography will track retinal layers and vessel density. These assessments occur before treatment, immediately after the first session, after 12 days of training, and 22 days post-treatment to monitor lasting effects and safety. Total participation spans several weeks to capture recovery progress.

Light Stimulation to Improve Visual Function After Optic Neuritis in Persons with Multiple Sclerosis