Actively Recruiting
Assessing Effectiveness of Light Therapy and Occupational Therapy for Fatigue Management in Patients With Genitourinary Cancers
Led by City of Hope Medical Center ยท Updated on 2025-12-24
224
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
C
City of Hope Medical Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to evaluate the effects of light therapy and occupational therapy in managing cancer-related fatigue (CRF) in patients with genitourinary cancers such as prostate, kidney, and bladder cancer. The study explores whether combining these two approaches can improve fatigue, offering a low burden and accessible intervention to support cancer patients. Occupational therapy is commonly used but often underutilized in cancer care, and this study seeks to assess its added benefit alongside light therapy. Participants are randomly assigned to one of four groups: one group uses bright white light therapy glasses for 30 minutes every morning for three months with follow-up sessions, another group receives six one-hour occupational therapy sessions, a third group receives both light therapy and occupational therapy, and the fourth group receives routine treatment and follow-up care with their oncologist. After these interventions, patients are followed for an additional three months to monitor outcomes. Throughout the study, participants complete questionnaires assessing fatigue levels and occupational performance at baseline, six weeks, and three months. Researchers monitor fatigue using the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue tool and evaluate occupational performance with the Canadian Occupational and Performance Measure (COPM). Safety and adherence are supported by follow-up visits, and the total participation duration is approximately six months from baseline through follow-up.
CONDITIONS
Brief Title
Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 and over
- Fluent in English
- Receiving active systemic therapy or radiotherapy
- Diagnosed with genitourinary cancer (prostate, kidney, bladder)
- Physician-assessed grade 1 or 2 fatigue at study entry
- Prognosis of at least six months
- Able and willing to provide informed consent
- Pre-screen fatigue score (FACIT-Fatigue) of 30 or less
You will not qualify if you...
- Severe sleep disorders such as narcolepsy
- Eye diseases limiting light processing (e.g., untreated cataracts, severe glaucoma, macular degeneration, blindness, retinal disorders)
- Severe psychological impairment (e.g., bipolar disorder, manic episodes)
- Currently working night shifts
- Prior use of light therapy for fatigue or depression
- Secondary cancer diagnosis within past 5 years
- Plans to travel across time zones during treatment
- Pregnancy
- Recent eye surgery causing irritation within past 6 months
- Sensitivity to light, epilepsy, or history of seizures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 3 months
Participants receive one of the study interventions: bright white light therapy using light glasses daily for 3 months, occupational therapy with 6 sessions, a combination of both, or routine treatment and usual care.
6 follow-up visits depending on intervention group
Duration - 3 months
Participants are monitored for 3 months after completing the intervention to assess fatigue and occupational performance.
Visits as part of routine follow-up care
Trial Site Locations
Total: 1 location
1
City of Hope Medical Center
Duarte, California, United States, 91010
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
4
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