Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05519878

Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

Led by City of Hope Medical Center · Updated on 2025-12-24

224

Participants Needed

1

Research Sites

234 weeks

Total Duration

On this page

Sponsors

C

City of Hope Medical Center

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This clinical trial evaluates light therapy and occupational therapy in improving cancer related fatigue (CRF) patients with genitourinary cancers. Light therapy is a non-pharmacological and evidence-based intervention for managing fatigue in cancer patients. The use of light therapy can provide a low burden, inexpensive, and easy to disseminate intervention approach that can potentially have a larger impact on CRF. In addition, occupational therapy is a standard, but often underutilized, component of the multi-disciplinary approach to cancer care. Using the combination of light therapy and occupational therapy may be effective in CRF management.

CONDITIONS

Official Title

Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 and over
  • Sufficiently fluent in English
  • On active treatment receiving systemic therapy (e.g., chemotherapy, immunotherapy, hormonal therapy) or radiotherapy
  • Diagnosed with genitourinary cancer (prostate, kidney, or bladder) with grade 1 or 2 fatigue based on physician assessment
  • Clinician assessed prognosis of six months or longer
  • Willing and able to provide informed consent independently
  • Pre-screen Functional Assessment of Cancer Therapy-Fatigue (FACIT-Fatigue) score of 30 or less
Not Eligible

You will not qualify if you...

  • Severe sleep disorders such as narcolepsy
  • Eye diseases limiting light processing (untreated cataracts, severe glaucoma, macular degeneration, blindness, pupil dilation problems, or other retinal disorders)
  • Severe psychological impairment (e.g., bipolar disorder or manic episodes)
  • Current employment in night shift work
  • Previous use of light therapy for fatigue or depressive symptoms
  • Secondary cancer diagnosis within the past 5 years
  • Plans to travel across time zones during treatment
  • Pregnancy
  • Recovering from eye surgery causing irritation within the past 6 months
  • Sensitivity to light, epilepsy, or history of seizures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

City of Hope Medical Center

Duarte, California, United States, 91010

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

4

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